Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy.
Niccolò Cusano University (UNICUSANO), Rome, Italy.
Dent Med Probl. 2022 Jul-Sep;59(3):461-474. doi: 10.17219/dmp/146133.
Dentistry as a profession should take into account the goals of sustainable development in daily practice and encourage the transition to a green economy. Consumers are becoming more conscious about the impact of self-care products, including toothpastes, on the environment. Organic toothpastes are considered very safe. A broad literature review was conducted to: (i) identify the ingredients in available organic toothpastes; (ii) classify them into active and inactive; and (iii) evaluate each ingredient's purpose and the adverse events that may be associated with its use. A comprehensive list of available organic toothpastes and their ingredients was compiled based on the products from the largest Italian organic supermarket chain (NaturaSì®) that is representative of the European market. Then, PubMed, Scopus and Google Scholar databases were searched to identify, classify and evaluate each ingredient. The final sample consisted of 46 organic toothpastes that included 156 ingredients; 139 (89.1%) and 17 (10.9%) were classified as active and inactive, respectively. Overall, 32 (20.5%) ingredients were associated with known adverse events. The results of this study indicate that organic toothpastes are highly biocompatible with oral cavity tissues. Careful product selection may help consumers avoid potential adverse effects that can be caused by ingredients such as polymers (e.g., polyethylene glycol) and carbomers, detergent agents (e.g., sodium lauryl sulfate), and triclosan. The lack of clinical studies should encourage the development of sufficient evidence to provide consumers with recommendations for daily use, based on both efficacy and biocompatibility.
口腔医学作为一门专业，在日常实践中应考虑可持续发展的目标，并鼓励向绿色经济转型。消费者对包括牙膏在内的自我护理产品对环境的影响的认识不断提高。有机牙膏被认为非常安全。进行了广泛的文献综述，以：（i）确定现有有机牙膏的成分；（ii）将它们分类为活性和非活性；（iii）评估每种成分的用途以及与其使用相关的不良事件。根据代表欧洲市场的最大意大利有机连锁超市（NaturaSì®）的产品，编制了现有有机牙膏及其成分的综合清单。然后，搜索了 PubMed、Scopus 和 Google Scholar 数据库，以识别、分类和评估每种成分。最终样本由 46 种有机牙膏组成，包含 156 种成分；139 种（89.1%）和 17 种（10.9%）分别被归类为活性和非活性。总体而言，有 32 种（20.5%）成分与已知不良事件有关。这项研究的结果表明，有机牙膏与口腔组织具有高度的生物相容性。仔细选择产品可能有助于消费者避免可能由聚合物（例如聚乙二醇）和卡波姆、清洁剂（例如月桂醇硫酸钠）和三氯生等成分引起的潜在不良影响。缺乏临床研究应鼓励开发足够的证据，根据功效和生物相容性为消费者提供日常使用建议。
