Suppr超能文献

基于 RNAi 的疗法:防治虾类病毒性疾病。

RNAi-Based Therapy: Combating Shrimp Viral Diseases.

机构信息

Department of Genetics and Fish Breeding, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh.

Department of Biotechnology, Sher-e-Bangla Agricultural University, Dhaka 1207, Bangladesh.

出版信息

Viruses. 2023 Oct 5;15(10):2050. doi: 10.3390/v15102050.

Abstract

Shrimp aquaculture has become a vital industry, meeting the growing global demand for seafood. Shrimp viral diseases have posed significant challenges to the aquaculture industry, causing major economic losses worldwide. Conventional treatment methods have proven to be ineffective in controlling these diseases. However, recent advances in RNA interference (RNAi) technology have opened new possibilities for combating shrimp viral diseases. This cutting-edge technology uses cellular machinery to silence specific viral genes, preventing viral replication and spread. Numerous studies have shown the effectiveness of RNAi-based therapies in various model organisms, paving the way for their use in shrimp health. By precisely targeting viral pathogens, RNAi has the potential to provide a sustainable and environmentally friendly solution to combat viral diseases in shrimp aquaculture. This review paper provides an overview of RNAi-based therapy and its potential as a game-changer for shrimp viral diseases. We discuss the principles of RNAi, its application in combating viral infections, and the current progress made in RNAi-based therapy for shrimp viral diseases. We also address the challenges and prospects of this innovative approach.

摘要

虾类养殖业已成为一项至关重要的产业,满足了全球对海鲜不断增长的需求。虾类病毒性疾病对水产养殖业构成了重大挑战,在全球范围内造成了重大经济损失。传统的治疗方法已被证明无法有效控制这些疾病。然而,RNA 干扰 (RNAi) 技术的最新进展为防治虾类病毒性疾病开辟了新的可能性。这项前沿技术利用细胞机制使特定的病毒基因沉默,从而阻止病毒的复制和传播。大量研究表明,基于 RNAi 的疗法在各种模式生物中具有有效性,为其在虾类健康中的应用铺平了道路。通过精确靶向病毒病原体,RNAi 有可能为防治虾类水产养殖中的病毒性疾病提供一种可持续且环保的解决方案。本文综述了基于 RNAi 的疗法及其作为虾类病毒性疾病变革者的潜力。我们讨论了 RNAi 的原理、其在防治病毒感染中的应用,以及在基于 RNAi 的虾类病毒性疾病疗法方面取得的最新进展。我们还讨论了这种创新方法面临的挑战和前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/249a/10612085/11f18616bacc/viruses-15-02050-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验