Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, USA.
Neurogastroenterol Motil. 2023 Dec;35(12):e14700. doi: 10.1111/nmo.14700. Epub 2023 Oct 27.
This mini-review summarizes the most recent literature regarding per-oral endoscopic myotomy for type III achalasia, emphasizing the poorly understood science of tailoring myotomy length during this procedure. In addition, special attention will be placed on the current subjective and objective biomarkers, such as the Eckardt score, used to evaluate treatment outcomes in this population to better contextualize the existing data on patient outcomes, as proposed by Low et al in the current issue of the Journal. Understanding the current treatment landscape for type III achalasia and identifying the key areas of research deficiencies will guide future investigation and management of this disease.
这篇迷你综述总结了最近关于经口内镜肌切开术治疗 III 型贲门失弛缓症的文献,重点介绍了在该手术中精确调整肌切开长度的相关科学知识。此外,本文还将特别关注目前用于评估该人群治疗效果的主观和客观生物标志物,例如 Eckardt 评分,以更好地理解 Low 等人在本期杂志中提出的关于患者结局的现有数据。了解 III 型贲门失弛缓症的当前治疗现状,并确定研究不足之处的关键领域,将有助于指导该疾病的未来研究和管理。