Department of Ophthalmology, Faculty of Medicine (for Girls), Al-Azhar University, Cairo, Egypt.
Int Ophthalmol. 2023 Dec;43(12):4945-4958. doi: 10.1007/s10792-023-02897-7. Epub 2023 Oct 28.
To investigate the link between the capsular bend and the morphological types and characteristics of posterior capsular opacification (PCO) using anterior segment optical coherence tomography.
Thirty eyes with PCO were examined, and three types of PCO were identified: pearl, fibrosis, and mixed. We assessed anterior capsular overlap, intraocular lens-capsule adhesion, and capsular bending. In addition to measuring the intraocular lens-posterior capsule distance and capsule bending angle (CBA), the PCO parameters (area, density, and score at 6-, 5-, and 3-mm intraocular lens optic regions) were recorded. The associations between capsular bend and PCO type and characteristics were investigated. A control group of 12 eyes without PCO was used to compare the study variables.
With p values greater than 0.001, there was a statistically significant difference in the mean PCO area and score at the 6-, 5-, and 3-mm optic zones in different PCO types, with the pearl type having the highest value, followed by the mixed type, and finally the fibrosis type. The PCO group had a significantly higher mean CBA than the control group (P = 0.001). CBA was positively related to intraocular lens-posterior capsule distance, PCO area, and PCO score at the 6-, 5-, and 3-mm zones (P = 0.001). The receiver operating characteristic curve's cut-off point for CBA was 96.85° when comparing PCO cases to controls. Partial overlap and incomplete adhesion were statistically more common in the PCO eyes than in the control (P = 0.001, 0.003, respectively).
PCO types and CBA have a strong relationship with PCO score and intraocular lens-posterior capsule space. In PCO's eyes, CBA has a cut-off value of 96.85°.
使用眼前节光学相干断层扫描研究囊袋弯曲与后发性白内障（PCO）形态类型和特征之间的关系。
检查 30 只患有 PCO 的眼睛，并确定三种 PCO 类型：珍珠样、纤维样和混合样。评估前囊重叠、人工晶状体-囊袋黏附以及囊袋弯曲。除了测量人工晶状体-后囊距离和囊袋弯曲角度（CBA）外，还记录 PCO 参数（在晶状体光学区 6、5 和 3mm 处的面积、密度和评分）。研究了囊袋弯曲与 PCO 类型和特征之间的关系。使用 12 只无 PCO 的对照组眼来比较研究变量。
具有统计学意义的差异（P 值均大于 0.001），在不同 PCO 类型中，PCO 面积和在 6、5 和 3mm 光学区的评分均值存在差异，珍珠样 PCO 的平均值最高，其次是混合样，最后是纤维样。与对照组相比，PCO 组的平均 CBA 显著更高（P=0.001）。CBA 与人工晶状体-后囊距离、PCO 面积和 PCO 在 6、5 和 3mm 区的评分呈正相关（P=0.001）。比较 PCO 病例和对照组时，CBA 的截断值为 96.85°。与对照组相比，PCO 眼的部分重叠和不完全黏附更为常见（P=0.001，0.003）。
PCO 类型和 CBA 与 PCO 评分和人工晶状体-后囊空间密切相关。在 PCO 眼中，CBA 的截断值为 96.85°。
