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术前 MRI 预测前交叉韧带损伤的生物标志物。

Biomarkers that Can Predict the Diagnosis of an Anterior Cruciate Ligament Injury on MR Images, Preoperatively.

机构信息

Kahramankazan State Hospital, Department of Orthopaedics and Traumatology, Ankara, Turkey.

Beytepe Murat Erdi Eker State Hospital, Department of Orthopaedics and Traumatology, Ankara, Turkey.

出版信息

Acta Chir Orthop Traumatol Cech. 2023;90(5):347-352.

PMID:37898499
Abstract

PURPOSE OF THE STUDY The competence of the anterior translation of tibia (ATT), posterior cruciate ligament angle (PCLA), and femorotibial rotation angle (FTRA) measured on MR images in predicting anterior cruciate ligament (ACL) injury was evaluated in this study. MATERIAL AND METHODS 266 patients who underwent diagnostic arthroscopy between 2015-2020 were included in this study. Age, gender, radiological fi ndings included ATT, PCLA, and FTRA were measured on preoperative MR images of all patients. RESULTS ACL tear was detected in 143 of patients and most of them were younger males. In ACL-R group, the ATT was 7 mm (-4-17 mm), PCLA value was 110º (52º-157º), and FTRA value was 5.8º (-5º-18º), while in ACL-I group, the ATT was approximately 5 mm (-4-12 mm), PCLA value was 122º (82º-162º) and FTRA value was 1.6º (-10.9º-10º) (p<0.001). ROCCurve test results showed that if ATT value was >6.05 mm (63% sensitivity, 65% specifi city) if PCLA value was <116.5º (65% sensitivity, 70% specifi city) and if FTRA value was >3.45º (73% sensitivity, 72% specifi city), these parameters could predict the probability of ACL tear, preoperatively. The Logistic Regression test results revealed that the PCLA and FTRA values could be the best markers to predict the probability of ACL tear, preoperatively. CONCLUSIONS This study results showed that the ATT, PCLA, and FTRA values could be used as predictive markers in diagnosis of ACL tear, preoperatively. Among these three values, it was concluded that the FTRA could have the highest sensitivity and specifi city ratios and the best predictive value. Key words: anterior cruciate ligament tear, magnetic resonance imaging, arthroscopy, rotational instability, femorotibial rotation angle, anterior translation of the tibia, posterior cruciate ligament angle.

摘要

研究目的 本研究旨在评估 MRI 图像上测量的胫骨前移位(ATT)、后交叉韧带角(PCLA)和股骨胫骨旋转角(FTRA)在预测前交叉韧带(ACL)损伤中的能力。

材料与方法 本研究纳入了 2015 年至 2020 年间接受诊断性关节镜检查的 266 名患者。所有患者均在术前 MRI 图像上测量年龄、性别、影像学发现,包括 ATT、PCLA 和 FTRA。

结果 在 143 名患者中发现 ACL 撕裂,其中大多数为年轻男性。在 ACL-R 组中,ATT 为 7 毫米(-4-17 毫米),PCLA 值为 110°(52°-157°),FTRA 值为 5.8°(-5°-18°),而在 ACL-I 组中,ATT 约为 5 毫米(-4-12 毫米),PCLA 值为 122°(82°-162°),FTRA 值为 1.6°(-10.9°-10°)(p<0.001)。ROC 曲线检验结果表明,如果 ATT 值>6.05 毫米(63%敏感度,65%特异度),PCLA 值<116.5°(65%敏感度,70%特异度),FTRA 值>3.45°(73%敏感度,72%特异度),这些参数可术前预测 ACL 撕裂的概率。Logistic 回归检验结果表明,PCLA 和 FTRA 值可作为术前预测 ACL 撕裂概率的最佳标志物。

结论 本研究结果表明,ATT、PCLA 和 FTRA 值可作为 ACL 撕裂术前的预测标志物。在这三个值中,FTRA 的敏感度和特异度比值最高,预测价值最好。

关键词

前交叉韧带撕裂、磁共振成像、关节镜、旋转不稳定、股骨胫骨旋转角、胫骨前移位、后交叉韧带角。

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