Research Computing at Information, Technology and Consulting, Dartmouth College, Hanover, NH, USA.
The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.
BMC Med Res Methodol. 2023 Oct 28;23(1):253. doi: 10.1186/s12874-023-02069-2.
Physician participation in clinical trials is essential for the progress of modern medicine. However, the demand for physician research partners is outpacing physicians' interest in participating in scientific studies. Understanding the factors that influence physician participation in research is crucial to addressing this gap.
In this study, we used a physician's social network, as constructed from patient billing data, to study if the research choices of a physician's immediate peers influence their likelihood to participate in scientific research. We analyzed data from 348 physicians across 40 hospitals. We used logistic regression models to examine the relationship between a physician's participation in clinical trials and the participation of their social network peers, adjusting for age, years of employment, and influences from other hospital facilities.
We found that the likelihood of a physician participating in clinical trials increased dramatically with the proportion of their social network-defined colleagues at their primary hospital who were participating ([Formula: see text] for a 1% increase in the proportion of participating peers, [Formula: see text]). Additionally, physicians who work regularly at multiple facilities were more likely to participate ([Formula: see text], [Formula: see text]) and increasingly so as the extent to which they have social network ties to colleagues at hospitals other than their primary hospital increases ([Formula: see text], [Formula: see text]). These findings suggest an inter-hospital peer participation process.
Our study provides evidence that the social structure of a physician's work-life is associated with their decision to participate in scientific research. The results suggest that interventions aimed at increasing physician participation in clinical trials could leverage the social networks of physicians to encourage participation. By identifying factors that influence physician participation in research, we can work towards closing the gap between the demand for physician research partners and the number of physicians willing to participate in scientific studies.
医师参与临床试验对于现代医学的发展至关重要。然而,对医师研究伙伴的需求已经超过了医师参与科学研究的兴趣。了解影响医师参与研究的因素对于解决这一差距至关重要。
在这项研究中,我们使用了从患者计费数据构建的医师社交网络,来研究医师的直接同行的研究选择是否会影响他们参与科学研究的可能性。我们分析了来自 40 家医院的 348 位医师的数据。我们使用逻辑回归模型来研究医师参与临床试验与他们社交网络同行参与的关系,同时调整年龄、就业年限以及来自其他医院设施的影响。
我们发现,医师参与临床试验的可能性随着其主要医院中社交网络定义的同事参与的比例显著增加([Formula: see text],同事参与比例增加 1%时,[Formula: see text])。此外,经常在多个设施工作的医师更有可能参与([Formula: see text],[Formula: see text]),并且随着他们与主要医院以外的同事在社交网络上的联系程度的增加而越来越有可能参与([Formula: see text],[Formula: see text])。这些发现表明存在一种医院间的同行参与过程。
我们的研究提供了证据表明,医师工作生活的社会结构与其参与科学研究的决策相关。结果表明,旨在增加医师参与临床试验的干预措施可以利用医师的社交网络来鼓励参与。通过确定影响医师参与研究的因素,我们可以努力缩小对医师研究伙伴的需求与愿意参与科学研究的医师人数之间的差距。