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去分化型子宫内膜癌转移至腋窝淋巴结:一例报告。

Dedifferentiated endometrial carcinoma metastasis to axillary lymph node: a case report.

机构信息

Wayne State University, Detroit, USA.

Department of Surgery, Henry Ford Health and Wayne State University Medical School, 2799 W Grand Boulevard, Detroit, MI, 48202, USA.

出版信息

J Med Case Rep. 2023 Oct 30;17(1):451. doi: 10.1186/s13256-023-04192-6.

Abstract

BACKGROUND

We present an unusual case of a left axillary lymph node metastasis from a primary dedifferentiated endometrial carcinoma. This pattern of metastasis is likely the result of circulating tumor cells reaching the node through its arterial blood supply.

CASE PRESENTATION

In this report, a 68-year-old white woman with a dedifferentiated endometrial carcinoma underwent a hysterectomy. She later developed an enlarged axillary lymph node due to metastatic dedifferentiated endometrial carcinoma, treated with chemotherapy and anti-programmed cell death protein 1 immunotherapy resulting in a complete clinical and radiological response.

CONCLUSION

A review of the literature reveals the rarity of blood-borne lymph node metastasis, especially with uterine carcinoma. Immunotherapy has shown promising results in the treatment of some subtypes of metastatic uterine carcinoma.

摘要

背景

我们报告了一例罕见的左侧腋窝淋巴结转移性腺分解型子宫内膜癌病例。这种转移模式可能是循环肿瘤细胞通过其动脉血液供应到达淋巴结的结果。

病例介绍

本报告介绍了一例 68 岁白人女性,患有去分化型子宫内膜癌,行子宫切除术。后来,由于转移性去分化型子宫内膜癌,她的腋窝淋巴结肿大,接受化疗和抗程序性细胞死亡蛋白 1 免疫治疗后,完全缓解了临床和影像学表现。

结论

文献回顾表明,血源性淋巴结转移,特别是子宫癌,非常罕见。免疫疗法已显示出在治疗某些亚型转移性子宫癌方面的良好效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/10614416/b17af708cb9e/13256_2023_4192_Fig1_HTML.jpg

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