用脱氧腺苷三磷酸的非对映硫代磷酸酯类似物对大肠杆菌DNA聚合酶I作用机制的研究。 - Suppr

Suppr

超能文献

A study of the mechanism of DNA polymerase I from Escherichia coli with diastereomeric phosphorothioate analogs of deoxyadenosine triphosphate.

作者信息

Burgers P M, Eckstein F

出版信息

J Biol Chem. 1979 Aug 10;254(15):6889-93.

PMID:378995

Abstract

摘要

相似文献

A study of the mechanism of DNA polymerase I from Escherichia coli with diastereomeric phosphorothioate analogs of deoxyadenosine triphosphate.用脱氧腺苷三磷酸的非对映硫代磷酸酯类似物对大肠杆菌DNA聚合酶I作用机制的研究。

J Biol Chem. 1979 Aug 10;254(15):6889-93.

A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate.一项关于T4 DNA聚合酶与脱氧腺苷三磷酸非对映体硫代磷酸酯类似物作用机制的研究。

J Biol Chem. 1982 Jul 10;257(13):7684-8.

Structure-function analysis of 3'-->5'-exonuclease of DNA polymerases.DNA聚合酶3'→5'核酸外切酶的结构-功能分析

Methods Enzymol. 1995;262:363-85. doi: 10.1016/0076-6879(95)62030-3.

Template-prime-dependent turnover of (Sp)-dATP alpha S by T4 DNA polymerase. The stereochemistry of the associated 3' goes to 5'-exonuclease.T4 DNA聚合酶对（Sp）-dATPαS的模板引发依赖性周转。相关3'至5'核酸外切酶的立体化学。

J Biol Chem. 1982 Jul 10;257(13):7689-92.

Effect of metal cations on misincorporation by E. coli DNA polymerases.金属阳离子对大肠杆菌DNA聚合酶错配掺入的影响。

Biochem Biophys Res Commun. 1977 Aug 8;77(3):854-60. doi: 10.1016/s0006-291x(77)80056-9.

Mechanistic studies on deoxyribonucleic acid dependent ribonucleic acid polymerase from Escherichia coli using phosphorothioate analogues. 2. The elongation reaction.

Biochemistry. 1979 Sep 18;18(19):4120-3. doi: 10.1021/bi00586a010.

Unambiguous determination of the stereochemistry of nucleotidyl transfer catalyzed by DNA polymerase I from Escherichia coli.大肠杆菌DNA聚合酶I催化的核苷酸转移立体化学的明确测定。

Biochemistry. 1981 Mar 3;20(5):1245-52. doi: 10.1021/bi00508a030.

Characterization of the action of Escherichia coli DNA polymerase I at incisions produced by repair endodeoxyribonucleases.大肠杆菌DNA聚合酶I在修复核酸内切脱氧核糖核酸酶产生的切口处的作用特性

J Biol Chem. 1982 Jan 10;257(1):575-83.

Separation of the enzyme catalyzing polymerization of deoxyribonucleoside diphosphates from the preparations of Escherichia coli DNA polymerase I.从大肠杆菌DNA聚合酶I制剂中分离催化脱氧核糖核苷二磷酸聚合的酶。

FEBS Lett. 1978 Feb 15;86(2):201-4. doi: 10.1016/0014-5793(78)80562-6.

The nucleotide analog 2-aminopurine as a spectroscopic probe of nucleotide incorporation by the Klenow fragment of Escherichia coli polymerase I and bacteriophage T4 DNA polymerase.核苷酸类似物2-氨基嘌呤作为大肠杆菌聚合酶I的克列诺片段和噬菌体T4 DNA聚合酶掺入核苷酸的光谱探针。

Biochemistry. 1995 Jul 18;34(28):9185-92. doi: 10.1021/bi00028a031.

引用本文的文献

Synthesis and Properties of α-Phosphate-Modified Nucleoside Triphosphates.α-磷酸酯修饰的核苷三磷酸的合成与性质。

Molecules. 2024 Aug 30;29(17):4121. doi: 10.3390/molecules29174121.

Controlled enzymatic synthesis of oligonucleotides.寡核苷酸的可控酶促合成

Commun Chem. 2024 Jun 18;7(1):138. doi: 10.1038/s42004-024-01216-0.

An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex.一种针对 SARS-CoV-2 复制酶复合物的抗外切酶链终止核苷酸类似物。

Nucleic Acids Res. 2024 Feb 9;52(3):1325-1340. doi: 10.1093/nar/gkad1194.

Biocatalytic Synthesis of Antiviral Nucleosides, Cyclic Dinucleotides, and Oligonucleotide Therapies.抗病毒核苷、环二核苷酸和寡核苷酸疗法的生物催化合成

JACS Au. 2022 Nov 30;3(1):13-24. doi: 10.1021/jacsau.2c00481. eCollection 2023 Jan 23.

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.观察正确和错误核苷酸插入可捕获隐藏的聚合酶保真度检查点。

Nat Commun. 2022 Jun 9;13(1):3193. doi: 10.1038/s41467-022-30141-w.

Artificial nucleic acid backbones and their applications in therapeutics, synthetic biology and biotechnology.人工核酸骨架及其在治疗、合成生物学和生物技术中的应用。

Emerg Top Life Sci. 2021 Nov 12;5(5):691-697. doi: 10.1042/ETLS20210169.

History of DNA polymerase β X-ray crystallography.DNA 聚合酶 β 的 X 射线晶体学历史。

DNA Repair (Amst). 2020 Sep;93:102928. doi: 10.1016/j.dnarep.2020.102928.

Revealing the role of the product metal in DNA polymerase β catalysis.揭示产物金属在DNA聚合酶β催化中的作用。

Nucleic Acids Res. 2017 Mar 17;45(5):2736-2745. doi: 10.1093/nar/gkw1363.

Divalent ions attenuate DNA synthesis by human DNA polymerase α by changing the structure of the template/primer or by perturbing the polymerase reaction.二价离子通过改变模板/引物的结构或干扰聚合酶反应来减弱人DNA聚合酶α的DNA合成。

DNA Repair (Amst). 2016 Jul;43:24-33. doi: 10.1016/j.dnarep.2016.05.017. Epub 2016 May 12.

Processive Incorporation of Deoxynucleoside Triphosphate Analogs by Single-Molecule DNA Polymerase I (Klenow Fragment) Nanocircuits.单分子DNA聚合酶I（克列诺片段）纳米电路对脱氧核苷三磷酸类似物的持续掺入

J Am Chem Soc. 2015 Aug 5;137(30):9587-94. doi: 10.1021/jacs.5b02074. Epub 2015 Jul 17.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验