Zhao Jing, Xu Hai-Tao, Yin Yuan, Li Yan-Xia, Zheng Ya-Juan
Department of Ophthalmology, The Second Hospital of Jilin University, Changchun 130022, Jilin Province, China.
World J Clin Cases. 2023 Sep 26;11(27):6573-6578. doi: 10.12998/wjcc.v11.i27.6573.
Overhanging filtering bleb is a common complication after trabeculectomy and surgical repair is an effective treatment when the patient presents with apparent symptoms. Filtering bleb relevant infection including in the filtering bleb itself and even endophthalmitis in some severe cases has been reported. However, corneal fungal infection after filtering bleb repair is rarely reported.
A 57-year-old Chinese man who had sensations of redness and foreign body sensations in the left eye 3 wk after repair of overhanging filtering bleb. 3 wk ago, due to sensations of a foreign body in the left eye for 3 years with worsening for 3 mo. The patient was diagnosed as overhanging filtering bleb and underwent a repair of overhanging filtering bleb. Postoperative, the filtering bleb formed well and the intraocular pressure is normal. But the patient gradually develop redness, pain and a grey infiltrate of the cornea in the eye. Finally it developed into fungal corneal ulcer. Through asking the medical history, we found the patient had irregularly self-medicated for years with glucocorticoid eye drops for years to relieve the foreign body sensation in the eye caused by filtering bleb overhanging. Because the glucocorticoid eye drops he used years ago had provide normal sensation to the eye. After 3 mo of anti-fungal treatment, the inflammation was controlled.
In addition to avoiding the development of overhanging filtering bleb after trabeculectomy, the present case report also suggests that clinicians should pay more attention to the patient's ocular self-medication history. Particularly in patients with a history of glaucoma or eye surgery. Because these patients may be exposed to more types of eye drops than other individuals, they may select the wrong medications for long-term use, based on their previous experience.
滤过泡渗漏是小梁切除术后常见的并发症,当患者出现明显症状时,手术修复是一种有效的治疗方法。已有报道称存在与滤过泡相关的感染,包括滤过泡本身的感染,在某些严重情况下甚至会发生眼内炎。然而,滤过泡修复术后角膜真菌感染鲜有报道。
一名57岁的中国男性,在修复滤过泡渗漏3周后出现左眼发红和异物感。3周前,因左眼有异物感3年,且在3个月内症状加重。患者被诊断为滤过泡渗漏,并接受了滤过泡渗漏修复术。术后,滤过泡形成良好,眼压正常。但患者逐渐出现眼红、疼痛以及角膜灰白色浸润,最终发展为真菌性角膜溃疡。通过询问病史,我们发现患者多年来一直不定期自行使用糖皮质激素眼药水来缓解滤过泡渗漏引起的眼部异物感。因为他多年前使用的糖皮质激素眼药水曾使眼睛感觉正常。经过3个月的抗真菌治疗,炎症得到控制。
除了避免小梁切除术后滤过泡渗漏的发生外,本病例报告还提示临床医生应更加关注患者的眼部自行用药史。特别是有青光眼或眼部手术史的患者。因为这些患者可能比其他人接触更多种类的眼药水,他们可能会根据以往经验长期选择错误的药物。