癫痫的神经刺激机制
Mechanisms of Neurostimulation for Epilepsy.
作者信息
Toprani Sheela, Durand Dominique M
机构信息
Neurology, Division of Epilepsy, University of California Davis, CA, USA.
Department of Biomedical Engineering, Neural Engineering Center, Case Western Reserve University, Cleveland, OH, USA.
出版信息
Epilepsy Curr. 2023 Oct 15;23(5):298-302. doi: 10.1177/15357597231191887. eCollection 2023 Sep-Oct.
Abstract
This review discusses the use of neurostimulation therapies for epilepsy treatment, including vagal nerve stimulation, responsive neurostimulation, and deep brain stimulation. Different therapeutic strategies and their underlying mechanisms are explored, with a focus on optimizing parameters for seizure reduction. The review also highlights the paradigm shift toward a more diverse and multimodal approach to deep brain neuromodulation.
摘要
本综述讨论了神经刺激疗法在癫痫治疗中的应用，包括迷走神经刺激、反应性神经刺激和深部脑刺激。探讨了不同的治疗策略及其潜在机制，重点是优化减少癫痫发作的参数。该综述还强调了深部脑神经调节向更加多样化和多模式方法的范式转变。
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