Posgrado en Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Av. Universidad 3000, Ciudad Universitaria, Coyoacán, Ciudad de México, C.P. 04510, México.
Unidad de Química en Sisal, Facultad de Química, Universidad Nacional Autónoma de México, Puerto de Abrigo s/n, Sisal, Yucatán, México.
Bull Environ Contam Toxicol. 2023 Oct 31;111(5):60. doi: 10.1007/s00128-023-03788-4.
Benzophenone-3 (BP-3) is an active ingredient in sunscreen lotions and personal-care products that protects against the damaging effects of ultraviolet rays. Given its worldwide dissemination, it has been linked with harmful effects on aquatic biota; however, its impact is not fully understood calling for further studies. To understand the impacts on an important economically and ecologically species, we evaluated the toxicity of BP-3 during the embryonic development of Octopus maya. Embryos were exposed to increasing concentrations of up to 500 µg BP-3/L until hatching. Antioxidant enzyme activities, oxidative-stress indicators, and B-esterases activities were measured at different developmental phases (organogenesis, activation, and growth). There were no significant differences between treatments, suggesting the lack of production of toxic metabolites that may be related to a protective chorion, an underdeveloped detoxification system, and the experimental conditions that limited phototoxicity.
二苯甲酮-3（BP-3）是防晒霜和个人护理产品中的一种有效成分，可防止紫外线的有害影响。鉴于其在全球范围内的传播，它已与对水生生物群的有害影响联系在一起；然而，其影响尚未完全了解，需要进一步研究。为了了解对一种重要的经济和生态物种的影响，我们评估了 BP-3 在章鱼玛雅胚胎发育过程中的毒性。胚胎在孵化前暴露于高达 500 µg BP-3/L 的递增浓度下。在不同的发育阶段（器官发生、激活和生长）测量抗氧化酶活性、氧化应激指标和 B-酯酶活性。处理之间没有显着差异，这表明没有产生可能与保护性卵壳、未充分发育的解毒系统以及限制光毒性的实验条件有关的有毒代谢物。
