Department of Ophthalmology, University of Paris Est-Créteil, Créteil, France.
Eur J Ophthalmol. 2024 Mar;34(2):NP126-NP130. doi: 10.1177/11206721231211419. Epub 2023 Oct 31.
We describe a report of three cases of bilateral Peripapillary Hyperreflective Ovoid Mass-Like Structures (PHOMS), their respective multimodal imaging, and retinal nerve fiber layer (RNFL) analysis over time.
We performed an elaborated multimodal imaging of three pediatric patients with PHOMS. We performed a visual acuity testing, followed by a biomicroscopic and fundus examination, an additional Optical Coherence Tomography (OCT), fundus autofluorescence (FAF), infra-red (IR), fluorescein angiography (FA), Scanning laser Ophtalmoscopy (SLO), and retro-mode imaging. Furthermore, we analyzed RNFL thickness over several consecutive visits.
The multimodal approach exhibited similar characteristics of PHOMS in all eyes, namely a torus-like shaped that was particularly demarcated and well visualized using SLO and retro-mode tool. In all the eyes, we found a downward trend of the RNFL over time. In both the right and left eye, RNFL at presentation averaged at 152.33 ± 25.42 and 130 ± 18.33 microns, respectively. Several weeks after, it averaged at 142 ± 30.34 and 125.67 ± 14.84 microns, respectively.
Our report shows a thinning trend of the RNFL thickness over time in patients with PHOMS.
我们描述了三例双侧视盘周围高反射性类椭圆形肿块（PHOMS）的病例报告，以及它们各自的多模态成像和视网膜神经纤维层（RNFL）随时间的分析。
我们对三例 PHOMS 患儿进行了详细的多模态成像。我们进行了视力测试，然后进行了生物显微镜和眼底检查，以及额外的光学相干断层扫描（OCT）、眼底自发荧光（FAF）、近红外（IR）、荧光素血管造影（FA）、扫描激光检眼镜（SLO）和后模式成像。此外，我们分析了几个连续就诊时的 RNFL 厚度。
多模态方法在所有眼中均表现出 PHOMS 的相似特征，即环型形状，使用 SLO 和后模式工具可特别清晰地显示。在所有眼中，我们发现 RNFL 随时间呈下降趋势。右眼和左眼的 RNFL 在初次就诊时的平均值分别为 152.33 ± 25.42 和 130 ± 18.33 微米，数周后分别为 142 ± 30.34 和 125.67 ± 14.84 微米。
我们的报告显示，PHOMS 患者的 RNFL 厚度随时间呈变薄趋势。
