Wang Fubin
Department of Ophthalmology, Shanghai Bright Eye Hospital, Shanghai, 200336, People's Republic of China.
Int Med Case Rep J. 2024 Oct 11;17:843-847. doi: 10.2147/IMCRJ.S473185. eCollection 2024.
Spontaneous focal hemorrhage of optic disc in peripapillary hyperreflective ovoid mass-like structures (PHOMS) is rare. This study reports the image features of two cases of spontaneous hemorrhage of an optic disc in PHOMS.
: A 51-year-old woman complained of visual fatigue for 1 week. Small patchy hemorrhage was observed in the optic disc of the right eye. : A 17-year-old female presented with complaints of experiencing floaters in the left eye for a duration of 1 day. Small patchy hemorrhage was observed in the left optic disc. The patients underwent the color fundus photograph (CFP), fundus autofluorescence (FAF), spectral-domain optical coherence tomography (SD-OCT), optical coherence tomography angiography (OCTA), and Minimum intensity projection (Min-IP) images.
: The right eye showed a small patchy hemorrhage of optic disc. PHOMS on SD-OCT of both eyes exhibited an ovoid shape and manifested as peripapillary hyperreflective bright regions on en-face Min-IP image, the active blood flow signal of PHOMS was detected on SD-OCT/OCTA and FAF revealed a hypofluorescent. The optic cup-to-disc (C/D) ratio of both eyes was 0.06, respectively. : Small patchy hemorrhage was observed in the left optic disc and FAF showed hypofluorescence. PHOMS on SD-OCT of the left eye showed an ovoid shape and manifested as peripapillary hyperreflective bright regions on en-face Min-IP image, the active blood flow signal of PHOMS was detected on SD-OCT/OCTA. C/D in the right eye was 0.4.
Spontaneous focal hemorrhage of optic disc may occur in PHOMS. The space-occupying effect of PHOMS may lead to compression of surrounding tissues, resulting in the optic disc congestion and a reduced C/D ratio, thereby involving the microvascular system of the optic disc.
视乳头周围高反射卵圆状肿块样结构(PHOMS)中视盘的自发性局灶性出血较为罕见。本研究报告了两例PHOMS中视盘自发性出血的影像特征。
一名51岁女性主诉视觉疲劳1周。右眼视盘可见小片状出血。一名17岁女性主诉左眼出现飞蚊症1天。左眼视盘可见小片状出血。患者接受了彩色眼底照相(CFP)、眼底自发荧光(FAF)、频域光学相干断层扫描(SD-OCT)、光学相干断层扫描血管造影(OCTA)及最小强度投影(Min-IP)成像检查。
右眼视盘出现小片状出血。双眼SD-OCT上的PHOMS呈卵圆状,在正面Min-IP图像上表现为视乳头周围高反射明亮区域,SD-OCT/OCTA检测到PHOMS的活跃血流信号,FAF显示低荧光。双眼的杯盘比(C/D)均为0.06。左眼视盘可见小片状出血,FAF显示低荧光。左眼SD-OCT上的PHOMS呈卵圆状,在正面Min-IP图像上表现为视乳头周围高反射明亮区域,SD-OCT/OCTA检测到PHOMS的活跃血流信号。右眼C/D为0.4。
PHOMS中可能发生视盘的自发性局灶性出血。PHOMS的占位效应可能导致周围组织受压,引起视盘充血和C/D比值降低,进而累及视盘的微血管系统。