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儿科造血干细胞移植(HSCT)的毒性应激和创伤模式:创建响应干预模型。

Patterns of toxic stress and trauma for pediatric Hematopoietic Stem Cell Transplantation (HSCT): creating a model of responsive intervention.

机构信息

Postdoctoral Research Scholar, Indiana University, School of Nursing, Indianapolis, IN, USA.

Professor of Music Therapy, Temple University, Boyer College of Music and Dance, Philadelphia, PA, USA.

出版信息

J Psychosoc Oncol. 2024;42(4):457-472. doi: 10.1080/07347332.2023.2276966. Epub 2023 Oct 30.

DOI:10.1080/07347332.2023.2276966
PMID:37904534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11058118/
Abstract

BACKGROUND

It is well documented that invasive medical treatment, such as Hematopoietic Stem Cell Transplant (HSCT), can be stressful and potentially traumatic for children, leading to Post Traumatic Stress Disorder (PTSD) or Post Traumatic Stress Symptoms (PTSS) after treatment. Despite this evidence, little is known about the patterns of stress and trauma that develop throughout the HSCT admission.

PURPOSE

To examine patterns of toxic stress and trauma that develop throughout the pediatric HSCT admission and understand how music therapists, as members of the interdisciplinary psychosocial care team, may proactively intervene to mitigate the impact of traumatic experiences.

METHOD

A two-phase retrospective longitudinal multi-case design was used with a combination of time series and template analyses.

SAMPLE

The sample included 14 pediatric patients (aged 0-17) undergoing HSCT at a large pediatric hospital in the Midwestern United States.

FINDINGS

The results were identifiable patterns of toxic stress and trauma and a model of care for music therapy that is responsive to the identified patterns.

摘要

背景

有大量文献记录表明,造血干细胞移植(HSCT)等有创性的医学治疗可能会给儿童带来压力和潜在的创伤,导致治疗后出现创伤后应激障碍(PTSD)或创伤后应激症状(PTSS)。尽管有这些证据,但对于 HSCT 住院期间发生的压力和创伤模式知之甚少。

目的

探讨儿科 HSCT 住院期间发生的毒性压力和创伤模式,并了解音乐治疗师作为跨学科心理社会关怀团队的成员,如何主动干预以减轻创伤经历的影响。

方法

采用两阶段回顾性纵向多案例设计,结合时间序列和模板分析。

样本

该样本包括在美国中西部一家大型儿科医院接受 HSCT 的 14 名儿科患者(年龄 0-17 岁)。

结果

研究结果确定了毒性压力和创伤的模式,并提出了一种针对音乐治疗的护理模式,该模式对确定的模式具有响应性。

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本文引用的文献

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Early childhood stress responses to psychosocial stressors: The state of the science.儿童早期对心理社会应激源的应激反应:科学现状。
Dev Psychobiol. 2022 Nov;64(7):e22320. doi: 10.1002/dev.22320.
2
Experiences of Pain in Hospitalized Children During Hematopoietic Stem Cell Transplantation Therapy.住院患儿造血干细胞移植治疗期间的疼痛体验。
Qual Health Res. 2021 Oct;31(12):2247-2259. doi: 10.1177/10497323211034161. Epub 2021 Aug 7.
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External locus-of-control partially mediates the association between cumulative trauma exposure and posttraumatic stress symptoms among adolescents from diverse background.外部控制源部分中介了不同背景青少年的累积创伤暴露与创伤后应激症状之间的关系。
Anxiety Stress Coping. 2021 Nov;34(6):626-644. doi: 10.1080/10615806.2021.1891224. Epub 2021 Mar 2.
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A Survey of Music Therapists Working in Pediatric Medical Settings in the United States.美国儿科医疗环境中音乐治疗师工作情况调查
J Music Ther. 2020 Feb 25;57(1):34-65. doi: 10.1093/jmt/thz019.
5
Screening for Family Psychosocial Risk in Pediatric Hematopoietic Stem Cell Transplantation with the Psychosocial Assessment Tool.使用心理社会评估工具对儿科造血干细胞移植中的家庭心理社会风险进行筛查。
Biol Blood Marrow Transplant. 2019 Jul;25(7):1374-1381. doi: 10.1016/j.bbmt.2019.03.012. Epub 2019 Mar 14.
6
Music therapy supported the health-related quality of life for children undergoing haematopoietic stem cell transplants.音乐治疗有助于提高进行造血干细胞移植的儿童的健康相关生活质量。
Acta Paediatr. 2018 Nov;107(11):1986-1994. doi: 10.1111/apa.14515. Epub 2018 Aug 23.
7
Studying complexity in health services research: desperately seeking an overdue paradigm shift.研究卫生服务研究中的复杂性:迫切需要一场姗姗来迟的范式转变。
BMC Med. 2018 Jun 20;16(1):95. doi: 10.1186/s12916-018-1089-4.
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The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis.多种不良童年经历对健康的影响:系统评价和荟萃分析。
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Current Use and Trends in Hematopoietic Cell Transplantation in the United States.美国造血细胞移植的当前应用与趋势
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