Higginbotham E J, Richardson T M
Br J Ophthalmol. 1986 Nov;70(11):837-9. doi: 10.1136/bjo.70.11.837.
The comparative response of exfoliation (EF) glaucoma and primary open-angle glaucoma (POAG) to laser trabeculoplasty (LTP) was studied retrospectively. The effectiveness of argon laser trabeculoplasty (LTP) was compared in 26 eyes of patients with EF glaucoma (uncontrollable by maximally tolerated medical therapy) and 28 eyes of patients with POAG (controls). 64% of the POAG group and 46% of the EF glaucoma group received treatment of the entire angle in two divided sessions in order to reduce the intraocular pressure (IOP) to less than or equal to 22 mmHg. All second treatments were performed at least four to six weeks after the initial session. Evaluation of the postoperative course of IOP by means of the Kaplan-Meier curve for data analysis indicated that EF patients 'failed' at a faster rate than POAG patients after both the initial and consecutive laser treatments. The rate of failure in the EF group, however, was greater following the initial 180 degrees treatment. Although patients with EF glaucoma have a large initial reduction in intraocular pressure after LTP, to increase the probability of maintaining intraocular pressures of less than or equal to 22 mmHg consecutive 180 degrees treatments should be considered.
回顾性研究了剥脱性（EF）青光眼和原发性开角型青光眼（POAG）对激光小梁成形术（LTP）的相对反应。比较了氩激光小梁成形术（LTP）在26例EF青光眼患者（最大耐受药物治疗无法控制眼压）和28例POAG患者（对照组）眼中的有效性。为了将眼压（IOP）降低至小于或等于22 mmHg，POAG组64%和EF青光眼组46%的患者分两次对整个房角进行治疗。所有第二次治疗均在初次治疗后至少四至六周进行。通过Kaplan-Meier曲线分析眼压术后过程表明，在初次和连续激光治疗后，EF患者眼压“失控”的速度比POAG患者更快。然而，在初次180度治疗后，EF组的眼压失控率更高。尽管EF青光眼患者在LTP后眼压最初会大幅下降，但为了提高将眼压维持在小于或等于22 mmHg的概率，应考虑连续进行180度治疗。
