原发性开角型青光眼与剥脱性青光眼的选择性激光小梁成形术比较
Comparison of selective laser trabeculoplasty (SLT) in primary open angle glaucoma and pseudoexfoliation glaucoma.
作者信息
Ayala Marcelo, Chen Enping
机构信息
Glaucoma Department, St Erik Eye Hospital, Karolinska Institutet, Stockholm, Sweden.
出版信息
Clin Ophthalmol. 2011;5:1469-73. doi: 10.2147/OPTH.S25636. Epub 2011 Oct 12.
BACKGROUND AND OBJECTIVE
The aim of the present study was to compare intraocular pressure (IOP) reduction and inflammation after selective laser trabeculoplasty (SLT) treatment in patients suffering from primary open angle (POAG) vs pseudoexfoliative (PXFG) glaucoma.
STUDY DESIGN/PATIENTS AND METHODS: Sixty patients (60 eyes) participated in the study. Glaucoma patients (POAG or PXFG) scheduled for treatment with SLT were included. Inflammation was measured with a laser flare meter (Kowa FM-500). Measurements were made before SLT and 2 hours, 1 week, and 1 month after SLT treatment. IOP was also checked at the same time intervals.
RESULTS
Inflammation after SLT showed no significant difference between the groups (t-test, before: P = 0.16; 2 hours: P = 0.14; 1 week: P = 0.12; and 1 month: P = 0.36). IOP reduction was the same in both groups (t-test, P = 0.27).
CONCLUSION
SLT safely reduces IOP in both POAG and PXFG. Pseudoexfoliation does not seem to be a risk factor for post-laser complications.
背景与目的
本研究旨在比较原发性开角型青光眼（POAG）与假性剥脱性青光眼（PXFG）患者接受选择性激光小梁成形术（SLT）治疗后的眼压降低情况及炎症反应。
研究设计/患者与方法：60例患者（60只眼）参与了本研究。纳入计划接受SLT治疗的青光眼患者（POAG或PXFG）。使用激光 flare 仪（Kowa FM - 500）测量炎症反应。在SLT治疗前以及治疗后2小时、1周和1个月进行测量。同时在相同时间间隔检查眼压。
结果
SLT治疗后的炎症反应在两组之间无显著差异（t检验，治疗前：P = 0.16；2小时：P = 0.14；1周：P = 0.12；1个月：P = 0.36）。两组的眼压降低情况相同（t检验，P = 0.27）。
结论
SLT可安全降低POAG和PXFG患者的眼压。假性剥脱似乎不是激光治疗后并发症的危险因素。
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