Adam Maia, Moran James K, Kippe Yann David, Schouler-Ocak Meryam, Bermpohl Felix, Gutwinski Stefan, Goldschmidt Thomas
Psychiatrische Universitätsklinik der Charité im St. Hedwig Krankenhaus, Berlin, Germany.
Front Psychiatry. 2023 Oct 12;14:1240703. doi: 10.3389/fpsyt.2023.1240703. eCollection 2023.
While numerous studies have identified an increase in symptoms of depression as well as anxiety and distress due to the COVID-19 pandemic, relatively few studies have investigated the new-onset of psychiatric diseases during the pandemic.
This study focuses on the number of psychiatric new-onset diagnoses in a psychiatric emergency department (pED) in Berlin, Germany during the second wave of the pandemic (i.e. from 09/15/2020 to 03/01/2021 = COVID-19-period) compared to pre-pandemic times (09/15/2019 to 03/01/2020 = control period). We focused on diagnostic subgroups and performed logistic regression analysis to investigate potential risk groups based on covariables such as age, gender, homelessness, attending in police custody and familial relationship.
Overall, there was a 59.7% increase in new-onset psychiatric diagnoses during the COVID-19-period. Increases in the following diagnoses were observed: new-onset of substance-related and addictive disorders (+192.5%), depressive disorders (+115.8%), schizophrenia spectrum and psychotic disorders (+113.3%) and anxiety disorders (+63.6%). These diagnostic subgroups, together with attending in police custody, were found to predict pED presentations with new-onset during the COVID-19-period. Interestingly, in the group of new-onset psychiatric diseases in the COVID-19-period, higher amounts of job loss and living alone as well as a relative decrease in familial relationships were observed.
COVID-19 infections and post-COVID-19 syndrome are unlikely to have played a substantial role in the increase of new-onset diseases in this study. Conclusion: Our findings underline the role of indirect factors in new-onset of psychiatric diseases during the pandemic and should be a caveat for future pandemic control policies.
虽然众多研究已确定，由于新冠疫情，抑郁症状以及焦虑和痛苦有所增加，但相对较少的研究调查了疫情期间新发精神疾病情况。
本研究聚焦于德国柏林一家精神科急诊科（pED）在疫情第二波期间（即从2020年9月15日至2021年3月1日 = 新冠疫情期）与疫情前时期（2019年9月15日至2020年3月1日 = 对照期）相比的精神科新发诊断数量。我们关注诊断亚组，并进行逻辑回归分析，以基于年龄、性别、无家可归、被警方拘留以及家庭关系等协变量调查潜在风险群体。
总体而言，在新冠疫情期新发精神科诊断增加了59.7%。观察到以下诊断的增加：物质相关及成瘾性障碍新发病例（+192.5%）、抑郁障碍（+115.8%）、精神分裂症谱系及精神病性障碍（+113.3%）和焦虑障碍（+63.6%）。这些诊断亚组以及被警方拘留被发现可预测新冠疫情期的新发pED就诊情况。有趣的是，在新冠疫情期新发精神疾病组中，观察到失业和独居的情况较多，以及家庭关系相对减少。
新冠感染和新冠后综合征在本研究中新发病例增加中不太可能起主要作用。结论：我们的研究结果强调了间接因素在疫情期间新发精神疾病中的作用，应为未来的疫情防控政策提供警示。
