Department of Biotechnological and Applied Clinical Sciences (DISCAB), University of L' Aquila, Via Vetoio, (Coppito 2), L' Aquila, 67100, Italy.
Department of Public Health and Infectious Diseases, "La Sapienza" University of Rome, Rome, 00100, Italy.
BMC Psychiatry. 2024 Oct 8;24(1):658. doi: 10.1186/s12888-024-06078-3.
This study examined psychiatric hospitalisation patterns in San Salvatore Hospital in L' Aquila (Italy), during two major crises: the 2009 earthquake and the COVID-19 pandemic lockdown. The investigation spans two four-year periods, from 2008 to 2011 and from 2019 to 2022, with a focus on the trimester around the earthquake and the first wave/lockdown of the pandemic.
We analysed weekly psychiatric unit admissions of adults diagnosed with schizophrenia spectrum disorder, major depression, bipolar disorder, and alcohol/substance use disorder. Four-year periods around the Earthquake and COVID-19 Lockdown were divided into sixteen trimesters, and Generalised linear models were used to analyse the relationship between weekly hospitalisation frequency and trimesters by diagnosis using a Poisson distribution.
A total of 1195 and 1085 patients were admitted to the psychiatric ward in the 2008-2011 and 2019-2022 periods, respectively. Weekly hospitalisations in the earthquake trimester were lower than during the previous one for all diagnoses (schizophrenia spectrum: -41.9%, p = 0.040; major depression: -56.7%, p = 0.046; bipolar disorder: -69.1%, p = 0.011; alcohol/substance use disorder: -92.3%, p = 0.013). This reduction persisted for 21, 18, and 33 months after the earthquake for schizophrenia spectrum, bipolar, and alcohol/substance use disorders, respectively. Contrarily, patterns of weekly admissions around the COVID-19 lockdown remained substantially stable in the short term. However, a consistent long-term hospitalisation increase for all diagnoses characterised the first half of 2022 (the cessation of anti-COVID-19 measures; schizophrenia spectrum: +68.6%, p = 0.014; major depression: +133.3%, p = 0.033; bipolar disorder: +180.0%, p = 0.034; alcohol/substance use disorder: +475.0%, p = 0.001).
The present study indicated that exposure to major health crises can have both short- and long-term effects on psychiatric ward admission, holding significant implications for current and future major health emergency management strategies.
本研究考察了意大利拉奎拉圣萨尔瓦托雷医院在两次重大危机期间的精神病住院模式:2009 年地震和 COVID-19 大流行封锁。调查跨越了两个四年期,分别为 2008 年至 2011 年和 2019 年至 2022 年,重点关注地震前后和大流行第一波/封锁的 trimester。
我们分析了成年人被诊断为精神分裂症谱系障碍、重度抑郁症、双相情感障碍和酒精/物质使用障碍的每周精神病区入院情况。地震和 COVID-19 封锁的四年期分为十六个 trimester,使用广义线性模型,通过泊松分布,以诊断为依据,分析每周住院频率与 trimester 之间的关系。
在 2008-2011 年和 2019-2022 年期间,分别有 1195 名和 1085 名患者入住精神病病房。与前一个 trimester 相比,地震 trimester 的每周住院率在所有诊断中均较低(精神分裂症谱系:-41.9%,p=0.040;重度抑郁症:-56.7%,p=0.046;双相情感障碍:-69.1%,p=0.011;酒精/物质使用障碍:-92.3%,p=0.013)。这种减少在地震后分别持续了 21、18 和 33 个月。相比之下,COVID-19 封锁期间的每周入院模式在短期内基本保持稳定。然而,所有诊断的长期住院率增加在 2022 年上半年一直持续(停止抗 COVID-19 措施;精神分裂症谱系:+68.6%,p=0.014;重度抑郁症:+133.3%,p=0.033;双相情感障碍:+180.0%,p=0.034;酒精/物质使用障碍:+475.0%,p=0.001)。
本研究表明,暴露于重大健康危机可能对精神病区入院产生短期和长期影响,这对当前和未来的重大卫生应急管理策略具有重要意义。