General Surgery, Cancer Center, Department of Breast Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou, Zhejiang, China.
The second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
BMC Musculoskelet Disord. 2023 Oct 31;24(1):853. doi: 10.1186/s12891-023-06992-9.
Pathological fractures of the femoral neck caused by necrosis of the femoral head are extremely rare. Here, we report a rare case of bilateral femoral head osteonecrosis extending to the femoral neck, with bilateral pathological fractures of the femoral neck occurring within a short period of time.
A 65-year-old male with a 25-year history of daily consumption of 750 ml of liquor, presented with right hip pain after labor for 1 month. He subsequently sustained a right femoral neck fracture without trauma and underwent a right total hip arthroplasty. Two months later, he suffered a non-traumatic left femoral neck fracture and underwent a left total hip arthroplasty. Histopathological examination revealed osteonecrosis of the femoral head and neck, along with the presence of osteoclasts and granulomatous inflammation. Bone mineral density testing also showed osteoporosis. The bilateral femoral neck fractures were ruled out to be caused by any other pathological factors.
This is the first report of pathological fractures of the bilateral femoral neck caused by femoral head necrosis. During the literature review process, we found that this case conforms to the histological characteristics of rapidly destructive hip disease and analyzed the etiology of femoral head necrosis and the pathogenesis of femoral neck fractures.
由股骨头坏死引起的股骨颈病理性骨折极为罕见。在此,我们报告一例罕见的双侧股骨头骨坏死延伸至股骨颈病例,在短时间内双侧股骨颈相继发生病理性骨折。
一名 65 岁男性,有 25 年每日饮用 750 毫升白酒的病史,在劳作 1 个月后出现右髋部疼痛,随后无外伤发生右侧股骨颈骨折,并接受了右侧全髋关节置换术。2 个月后,他遭受了非外伤性左侧股骨颈骨折,并接受了左侧全髋关节置换术。组织病理学检查显示股骨头和颈骨坏死,同时存在破骨细胞和肉芽肿性炎症。骨矿物质密度测试也显示骨质疏松症。双侧股骨颈骨折排除了由任何其他病理因素引起的可能性。
这是首例由股骨头坏死引起的双侧股骨颈病理性骨折的报告。在文献复习过程中,我们发现该病例符合快速破坏性髋关节疾病的组织学特征,并分析了股骨头坏死的病因和股骨颈骨折的发病机制。