Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA.
Department of Orthopaedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Korean Med Sci. 2021 Mar 15;36(10):e65. doi: 10.3346/jkms.2021.36.e65.
Osteonecrosis of the femoral head (ONFH) is a devastating disease frequently leading to femoral head collapse and hip arthritis. Specifically, non-traumatic ONFH primarily affects young and middle-aged adults. Although compromised local circulation of the femoral head seems to be pathognomonic for the disease, the pathogenesis is perplexing and continues to be an area of scrutiny and research. Comprehension of the pathogenesis is of crucial importance for developing and guiding treatments for the disease. Therefore, we provide an up-to-date consensus on the pathogenesis of non-traumatic ONFH.
股骨头坏死（ONFH）是一种破坏性疾病，常导致股骨头塌陷和髋关节炎。具体而言，非创伤性 ONFH 主要影响年轻和中年成年人。尽管股骨头局部循环受损似乎是该疾病的特征，但发病机制令人费解，仍然是关注和研究的领域。理解发病机制对于开发和指导该疾病的治疗至关重要。因此，我们就非创伤性 ONFH 的发病机制提供了最新的共识。
