Kuroda Yujiro, Fujita Kosuke, Sugimoto Taiki, Uchida Kazuaki, Shimazu Taichi, Saito Junko, Arai Hidenori, Sakurai Takashi
Department of Prevention and Care Science, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, 474-8511, Aichi, Japan.
Division of Behavioural Sciences, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan.
Arch Public Health. 2023 Oct 31;81(1):191. doi: 10.1186/s13690-023-01205-0.
Multi-domain interventions effectively prevent dementia in clinical settings; however, their efficacy within local communities is unclear. This study assesses the feasibility of an adapted multi-domain intervention for dementia prevention in community-dwelling older adults.
The single-arm trial enrolls 60 participants from two Obu City communities, Japan.
participant retention in the adapted multi-domain intervention; secondary outcomes: health and implementation outcomes. Over 12 months, a team of researchers and public health nurse oversees the study in the first half, gradually shifting the management to public health nurses in the second half. Using the Framework for Reporting Adaptations and Modifications-Enhanced, the clinical programme is adjusted for the local community. It includes a 60-minute exercise and 30-minute group sessions, targeting lifestyle, diet, and social participation.
This pioneer study evaluates the feasibility of an adapted intervention programme for dementia prevention in a community setting. Challenges in disseminating dementia prevention programmes warrant further investigation into effective implementation as well as strategies and methods to appeal to the target population. Upon confirming this programme's feasibility, future studies can further evaluate its broader effectiveness.
The protocol is registered with the Clinical Trials Registry (UMIN-CTR) of the University Hospital's Medical Information Network, under registration number UMIN000050581.
多领域干预措施在临床环境中可有效预防痴呆症；然而，其在当地社区中的效果尚不清楚。本研究评估了一种针对社区居住的老年人预防痴呆症的适应性多领域干预措施的可行性。
这项单臂试验招募了来自日本大府市两个社区的60名参与者。
适应性多领域干预措施中的参与者留存率；次要结局：健康和实施结局。在12个月内，一组研究人员和公共卫生护士在前半年监督该研究，下半年逐渐将管理工作移交给公共卫生护士。使用《报告适应性和修改-增强版框架》，对临床方案进行了针对当地社区的调整。它包括一次60分钟的锻炼和30分钟的小组会议，目标是生活方式、饮食和社会参与。
这项开创性研究评估了在社区环境中预防痴呆症的适应性干预方案的可行性。在传播痴呆症预防方案方面的挑战值得进一步研究有效的实施方法以及吸引目标人群的策略和方法。在确认该方案的可行性后，未来的研究可以进一步评估其更广泛的有效性。
该方案已在大学医院医学信息网络的临床试验注册中心（UMIN-CTR）注册，注册号为UMIN000050581。
