Zhong Dayuan, Cheng Hui, Liu Huixian, Feng Shihui, Liu Yumei, Xiang Huier, Chen Jiaqi
Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou University of Chinese Medicine, Foshan, Guangdong, P. R. China.
Institute of Traditional Chinese Medicine, Jinan University, Guangzhou, Guangdong, P. R. China.
Electrophoresis. 2024 Feb;45(3-4):288-299. doi: 10.1002/elps.202300207. Epub 2023 Nov 1.
To gain a deeper understanding of the current status of research on Traditional Chinese Medicine (TCM) and nanoparticles, we conducted a bibliometric study. We conducted a literature search in the Web of Science (WOS) for publications related to TCM and nanoparticles from 1992 to 2023. The data, including countries of publication, research institutions, journals, citations, and keywords, were analyzed using the Bibliometrix R-4.0 software package. We performed an analysis to identify the co-occurrence of keywords in the documents including their titles and abstracts. From 2005 to 2023, a total of 309 publications were included, with an average annual growth rate of 4.25%. The majority of these publications were published in Q1 journals (72, 47.06%) and Q2 journals (45, 29.41%). Among the 309 publications, 22 articles (7.12%) had an impact factor greater than 10, while 78 articles (25.24%) had an impact factor greater than 5. The analysis of international collaboration networks revealed limited international cooperation, with most collaborations occurring between institutions in China, the United States, and Australia. These 309 publications involved a total of 438 research institutions, with Chinese research institutions being the most prolific contributors. In this study, a total of 309 publications were included, comprising 1142 author keywords and 1175 keywords plus. Factor analysis of the 1175 keywords plus revealed that they could be grouped into five categories: one category included terms such as "oxide" and "zinc," another category included terms like "lipid" and "acid," a third category included terms such as "improve" and "enhance," a fourth category included terms like "silica" and "mesoporous," and the fifth category included terms like "PLGA" and "immune." Research on nanoparticles in TCM has been gradually gaining popularity. Currently, most of the research in this field is conducted in China, with limited international collaboration. The majority of TCM nanoparticle research focuses on individual herbal compounds, while research on nanoparticle formulations of traditional herbal prescriptions is relatively scarce.
为了更深入地了解中医药（TCM）与纳米颗粒的研究现状，我们开展了一项文献计量学研究。我们在科学网（WOS）中进行文献检索，查找1992年至2023年期间与中医药和纳米颗粒相关的出版物。使用Bibliometrix R - 4.0软件包对数据进行分析，这些数据包括出版国家、研究机构、期刊、引用次数和关键词等。我们进行了分析，以确定文献（包括标题和摘要）中关键词的共现情况。2005年至2023年期间，共纳入309篇出版物，年均增长率为4.25%。这些出版物大多发表在Q1区期刊（72篇，占47.06%）和Q2区期刊（45篇，占29.41%）。在这309篇出版物中，22篇文章（占7.12%）的影响因子大于10，78篇文章（占25.24%）的影响因子大于5。国际合作网络分析显示国际合作有限，大多数合作发生在中国、美国和澳大利亚的机构之间。这309篇出版物共涉及438个研究机构，其中中国研究机构的贡献最为突出。在本研究中，共纳入309篇出版物，包括1142个作者关键词和1175个扩展关键词。对1175个扩展关键词的因子分析表明，它们可分为五类：一类包括“氧化物”和“锌”等术语；另一类包括“脂质”和“酸”等术语；第三类包括“改善”和“增强”等术语；第四类包括“二氧化硅”和“介孔”等术语；第五类包括“聚乳酸 - 羟基乙酸共聚物”（PLGA）和“免疫”等术语。中医药领域中纳米颗粒的研究逐渐受到关注。目前，该领域的大部分研究在中国进行，国际合作有限。大多数中医药纳米颗粒研究集中在单一草药化合物上，而对传统草药方剂纳米颗粒制剂的研究相对较少。
