Faculty of Pharmacy, Saint Joseph University of Beirut, Beirut, Lebanon.
Laboratoire de Pharmacologie, Pharmacie Clinique et Contrôle de Qualité des Médicaments, Saint Joseph University of Beirut, Beirut, Lebanon.
BMC Psychiatry. 2023 Nov 1;23(1):797. doi: 10.1186/s12888-023-05304-8.
The revised Opioid Risk Tool (ORT-OUD) is a brief, self-report scale designed to provide clinicians with a simple, validated method to screen for the risk of developing an Opioid Use Disorder (OUD) in patients without a prior history of substance abuse. This study aimed to translate and validate the Arabic version of ORT-OUD in the Lebanese population and assess its clinical validity in a sample of patients with OUD.
This cross-sectional study in the Lebanese population used several validated scales to assess the risk of OUD, including the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST). Other tools evaluated chronotype and sleep and mood disturbances. Principal component analysis with Varimax rotation was applied to assess ORT-OUD construct validity. Convergent validity with the Arabic version of ASSIST was evaluated. The ORT-OUD criterion validity was then assessed in a clinical sample of patients with OUD.
This study included 581 participants. The prevalence of the OUD risk in the Lebanese population using the ORT-OUD scale and the ASSIST-opioids scale was estimated at 14.5% and 6.54%, respectively. No items of the ORT-OUD were removed; all items converged over a solution of four factors with an eigenvalue > 1, explaining a total of 68.2% of the variance (Cronbach's alpha = 0.648). The correlation coefficients between the ORT-OUD total score and ASSIST subscales were as follows: ASSIST-opioids (r = 0.174; p = < 0.001), ASSIST-sedatives (r = 0.249; p < 0.001), and ASSIST-alcohol (r = 0.161; p = < 0.001). ORT-OUD clinical validation showed a correlation with ASSIST-opioids (r = 0.251; p = 0.093) and ASSIST-sedatives (r = 0.598; p < 0.001). Higher ORT-OUD scores were associated with a family and personal history of alcohol and substance consumption and higher insomnia and anxiety scores.
This study is the first to validate the Arabic version of ORT-OUD in the Lebanese population, an essential step towards improving the detection and management of OUD in this population.
修订后的阿片类药物风险工具（ORT-OUD）是一种简短的自我报告量表，旨在为临床医生提供一种简单、经过验证的方法，用于筛查没有滥用物质史的患者发生阿片类药物使用障碍（OUD）的风险。本研究旨在翻译并验证黎巴嫩人群中 ORT-OUD 的阿拉伯语版本，并在一组 OUD 患者中评估其临床有效性。
本研究是黎巴嫩人群中的横断面研究，使用了几种经过验证的量表来评估 OUD 风险，包括酒精、吸烟和物质使用参与筛查测试（ASSIST）。其他工具评估了睡眠时相和睡眠及情绪障碍。应用主成分分析和 Varimax 旋转来评估 ORT-OUD 的结构效度。评估阿拉伯语版本 ASSIST 的收敛效度。然后在一组 OUD 患者的临床样本中评估 ORT-OUD 的标准效度。
本研究纳入了 581 名参与者。使用 ORT-OUD 量表和 ASSIST-阿片剂量表估计黎巴嫩人群中 OUD 风险的患病率分别为 14.5%和 6.54%。没有删除 ORT-OUD 的任何项目；所有项目都收敛于一个特征值大于 1 的四个因素解中，共解释了 68.2%的方差（克朗巴赫α=0.648）。ORT-OUD 总分与 ASSIST 分量表的相关系数如下：ASSIST-阿片剂（r=0.174；p<0.001）、ASSIST-镇静剂（r=0.249；p<0.001）和 ASSIST-酒精（r=0.161；p<0.001）。ORT-OUD 的临床验证与 ASSIST-阿片剂（r=0.251；p=0.093）和 ASSIST-镇静剂（r=0.598；p<0.001）相关。较高的 ORT-OUD 评分与家庭和个人的酒精和物质使用史以及更高的失眠和焦虑评分相关。
本研究首次在黎巴嫩人群中验证了阿拉伯语版的 ORT-OUD，这是提高该人群 OUD 检测和管理水平的重要一步。
