棉酚对人及猴精子体外运动能力的影响。

Effects of gossypol on human and monkey sperm motility in vitro.

作者信息

Chongthammakun S, Ekavipat C, Sanitwongse B, Pavasuthipaisit K

出版信息

Contraception. 1986 Sep;34(3):323-31. doi: 10.1016/0010-7824(86)90013-2.

PMID:3791997

Abstract

The effects of gossypol acetic acid on human and monkey sperm motility in vitro were studied by using multiexposure photography technique. Human and monkey spermatozoa were inhibited by gossypol to different degrees. Monkey sperm were absolutely immotile within 15 min after 50 microM of gossypol was added, but motility of human spermatozoa was not completely suppressed by gossypol even at the highest concentration used and longest duration of exposure.

摘要

采用多次曝光摄影技术研究了醋酸棉酚对人及猴精子体外运动能力的影响。人及猴精子均受到不同程度的棉酚抑制。加入50微摩尔棉酚后，猴精子在15分钟内完全失去活动能力，但即使在所用最高浓度和最长暴露时间下，棉酚也未完全抑制人精子的运动能力。