Weiss W, Baur X
Chest. 1987 Jan;91(1):146-8. doi: 10.1378/chest.91.1.146.
We describe the identification and characterization of antigens of the pearl-oyster shell which caused hypersensitivity pneumonitis in a 42-year-old worker. He was occupationally exposed to the dust of this shell in the manufacture of different ornaments. In addition to a typical history, the diagnosis was confirmed through a workplace-related exposure test and high titres of antigen-specific IgG antibodies. By means of the immunoblot technique, several relevant antigens could be detected in the shell of the pearl-oyster. Control sera also contained immunoglobulins that bound to some electrophoretically separated bands; these could represent antibodies that react with lectin-like components in the shell in a nonimmunologic manner.
我们描述了一例42岁工人因珍珠贝贝壳抗原导致过敏性肺炎的病例，包括该抗原的鉴定和特征。他在制作不同饰品时职业性接触了这种贝壳的粉尘。除了典型病史外，通过与工作场所相关的暴露试验和高滴度的抗原特异性IgG抗体确诊。借助免疫印迹技术，在珍珠贝贝壳中检测到了几种相关抗原。对照血清中也含有与一些电泳分离条带结合的免疫球蛋白；这些可能代表以非免疫方式与贝壳中凝集素样成分反应的抗体。
