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Opioid, sedative, preadmission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study.英国成年危重症患者的阿片类药物、镇静剂、入院前用药和医源性戒断风险：一项时点患病率研究。
Int J Clin Pharm. 2023 Oct;45(5):1167-1175. doi: 10.1007/s11096-023-01614-9. Epub 2023 Jul 15.
2
International Analgesia and Sedation Weaning and Withdrawal Practices in Critically Ill Adults: The Adult Iatrogenic Withdrawal Study in the ICU.国际危重病成人镇痛镇静减停和撤药实践：重症监护成人医源性撤药研究。
Crit Care Med. 2023 Nov 1;51(11):1502-1514. doi: 10.1097/CCM.0000000000005951. Epub 2023 Jun 7.
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Multimodal, patient-centred symptom control: a strategy to replace sedation in the ICU.多模式、以患者为中心的症状控制：一种在重症监护病房替代镇静的策略。
Lancet Respir Med. 2023 Jun;11(6):506-509. doi: 10.1016/S2213-2600(23)00141-8. Epub 2023 May 12.
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Addressing opioid tolerance and opioid-induced hypersensitivity: Recent developments and future therapeutic strategies.解决阿片类药物耐受和阿片类药物诱发的超敏反应：最新进展和未来治疗策略。
Pharmacol Res Perspect. 2021 May;9(3):e00789. doi: 10.1002/prp2.789.
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Analgesia and sedation in patients with ARDS.急性呼吸窘迫综合征患者的镇痛与镇静。
Intensive Care Med. 2020 Dec;46(12):2342-2356. doi: 10.1007/s00134-020-06307-9. Epub 2020 Nov 10.
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Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients.镇静剂和阿片类药物对机械通气中触发和循环不同步的影响：一项来自危重病患者大型数据集的观察性研究。
Crit Care. 2019 Jul 5;23(1):245. doi: 10.1186/s13054-019-2531-5.
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Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU.成人 ICU 患者疼痛、躁动/镇静、谵妄、活动减少、睡眠障碍预防与管理临床实践指南。
Crit Care Med. 2018 Sep;46(9):e825-e873. doi: 10.1097/CCM.0000000000003299.
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Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit.成人重症监护病房疼痛、躁动和谵妄管理的临床实践指南。
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Adverse drug events associated with the use of analgesics, sedatives, and antipsychotics in the intensive care unit.与重症监护病房使用镇痛药、镇静剂和抗精神病药相关的药物不良反应。
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Protocolized intensive care unit management of analgesia, sedation, and delirium improves analgesia and subsyndromal delirium rates.规范化的重症加强护理病房镇痛、镇静和谵妄管理可提高镇痛和亚综合征性谵妄的发生率。
Anesth Analg. 2010 Aug;111(2):451-63. doi: 10.1213/ANE.0b013e3181d7e1b8. Epub 2010 Apr 7.

Scheduled intravenous opioids.

作者信息

McKenzie Cathrine, Skrobik Yoanna, Devlin John W

机构信息

National Institute of Health and Social Care Research (NIHR) Biomedical Research Centre, School of Medicine, Perioperative and Critical Care Theme and NIHR Applied Research Collaborative (ARC), University of Southampton, Wessex, Southampton, UK.

Pharmacy and Critical Care, University Hospital, Southampton NHS Foundation Trust, Southampton, UK.

出版信息

Intensive Care Med. 2023 Dec;49(12):1541-1543. doi: 10.1007/s00134-023-07254-x. Epub 2023 Nov 3.

DOI:10.1007/s00134-023-07254-x
PMID:37922011
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10709215/
Abstract
摘要