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多形核白细胞与有免疫沉积物的肾小球的黏附。

Attachment of polymorphonuclear leukocytes to glomeruli with immune deposits.

作者信息

Yamamoto T, Kihara I, Morita T, Oite T

出版信息

J Immunol Methods. 1979;26(4):315-23. doi: 10.1016/0022-1759(79)90177-7.

Abstract

A method for quantitative evaluation of a biological activity of immune complexes deposited in glomeruli is described. The activity reflects the activation of complement and is represented by the number of PMN attached to a glomerulus. It is possible to compare data from different individuals or different phases of glomerulonephritis. The complement component concerned is considered to be C3, activated through the classical or alternate pathway.

摘要

描述了一种定量评估沉积在肾小球中的免疫复合物生物活性的方法。该活性反映补体的激活,并以附着在肾小球上的中性粒细胞数量表示。可以比较来自不同个体或肾小球肾炎不同阶段的数据。所涉及的补体成分被认为是通过经典途径或替代途径激活的C3。

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