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多形核白细胞与有免疫沉积物的肾小球的黏附。

Attachment of polymorphonuclear leukocytes to glomeruli with immune deposits.

作者信息

Yamamoto T, Kihara I, Morita T, Oite T

出版信息

J Immunol Methods. 1979;26(4):315-23. doi: 10.1016/0022-1759(79)90177-7.

DOI:10.1016/0022-1759(79)90177-7
PMID:379225
Abstract

A method for quantitative evaluation of a biological activity of immune complexes deposited in glomeruli is described. The activity reflects the activation of complement and is represented by the number of PMN attached to a glomerulus. It is possible to compare data from different individuals or different phases of glomerulonephritis. The complement component concerned is considered to be C3, activated through the classical or alternate pathway.

摘要

描述了一种定量评估沉积在肾小球中的免疫复合物生物活性的方法。该活性反映补体的激活,并以附着在肾小球上的中性粒细胞数量表示。可以比较来自不同个体或肾小球肾炎不同阶段的数据。所涉及的补体成分被认为是通过经典途径或替代途径激活的C3。

相似文献

1
Attachment of polymorphonuclear leukocytes to glomeruli with immune deposits.多形核白细胞与有免疫沉积物的肾小球的黏附。
J Immunol Methods. 1979;26(4):315-23. doi: 10.1016/0022-1759(79)90177-7.
2
Role of divalent cations in binding polymorphonuclear leucocytes to glomeruli with immune complexes.二价阳离子在多形核白细胞通过免疫复合物与肾小球结合中的作用。
Clin Exp Immunol. 1980 Mar;39(3):583-7.
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Fatal immune complex glomerulonephritis without deposits.无沉积物的致死性免疫复合物肾小球肾炎
Johns Hopkins Med J. 1975 May;136(5):189-92.
4
Granulocyte adhesion to nephritic glomeruli through recognition of activated C4 and C3 in immune deposits.
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Br J Exp Pathol. 1983 Dec;64(6):660-9.
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Immunopathologic co-localization of MPO, IgG, and C3 in glomeruli in human MPO-ANCA-associated glomerulonephritis.人MPO-ANCA相关性肾小球肾炎中MPO、IgG和C3在肾小球中的免疫病理共定位。
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[Immune complex deposits in the glomeruli of membranous nephropathy, membranoproliferative glomerulonephritis and lupus nephritis].[膜性肾病、膜增生性肾小球肾炎和狼疮性肾炎肾小球中的免疫复合物沉积]
Nihon Jinzo Gakkai Shi. 1982 Jun;24(6):625-40.

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J Clin Lab Anal. 2005;19(1):16-21. doi: 10.1002/jcla.20049.
2
Role of divalent cations in binding polymorphonuclear leucocytes to glomeruli with immune complexes.二价阳离子在多形核白细胞通过免疫复合物与肾小球结合中的作用。
Clin Exp Immunol. 1980 Mar;39(3):583-7.
3
Bovine serum albumin (BSA) nephritis in rats II. Histological findings and complement activation by immune complex in SHR rats.
大鼠牛血清白蛋白(BSA)肾炎II. 自发性高血压大鼠(SHR)的组织学发现及免疫复合物介导的补体激活
Br J Exp Pathol. 1983 Dec;64(6):660-9.
4
Granulocyte adhesion to nephritic glomeruli through recognition of activated C4 and C3 in immune deposits.
Experientia. 1985 Nov 15;41(11):1456-7. doi: 10.1007/BF01950033.
5
Modification of immune complexes deposited in glomeruli in tissue sections treated with sulfonized gamma-globulin.用磺化γ球蛋白处理的组织切片中肾小球内沉积免疫复合物的修饰。
Clin Exp Immunol. 1986 Jun;64(3):623-8.