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马的焦性没食子酸中毒

Pyrogallol Toxicosis in Horses.

作者信息

Bischoff Karyn

机构信息

Department of Population Medicine and Diagnostic Sciences, Cornell University College of Veterinary Medicine, New York State Animal Health Diagnostic Center, PO Box 5786, Ithaca, NY 14853, USA.

出版信息

Vet Clin North Am Equine Pract. 2024 Apr;40(1):77-82. doi: 10.1016/j.cveq.2023.10.001. Epub 2023 Nov 3.

DOI:10.1016/j.cveq.2023.10.001
PMID:37923643
Abstract

Plants in the maple genus, Acer, and pistachio genus, Pistacia, have been reported to cause acute hemolysis in horses. The cause of hemolysis seems to be metabolism of gallic acids to the potent oxidant pyrogallol by enteric bacteria of the horse. Diagnosis is often tentative and circumstantial. Treatment is symptomatic and supportive and can include detoxification, fluid and electrolyte therapy, supplemental oxygen, and pain control. Corticosteroid and antioxidant therapies do not improve prognosis. Prognosis is guarded to poor but horses that survive 6 days postexposure are expected to recover.

摘要

据报道,枫树属(槭属)和黄连木属的植物会导致马匹急性溶血。溶血的原因似乎是马的肠道细菌将没食子酸代谢为强效氧化剂连苯三酚。诊断往往是初步的且基于间接证据。治疗是对症和支持性的,可包括解毒、液体和电解质疗法、补充氧气以及控制疼痛。皮质类固醇和抗氧化剂疗法并不能改善预后。预后谨慎至不佳,但暴露后存活6天的马匹有望康复。

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1
Pyrogallol Toxicosis in Horses.马的焦性没食子酸中毒
Vet Clin North Am Equine Pract. 2024 Apr;40(1):77-82. doi: 10.1016/j.cveq.2023.10.001. Epub 2023 Nov 3.
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