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胎儿前腹壁厚度作为诊断妊娠期糖尿病早期超声征象的诊断准确性

Diagnostic Accuracy of Fetal Anterior Abdominal Wall Thickness as an Early Sonographic Sign for Diagnosing Gestational Diabetes.

作者信息

Sabir Muhammad Sharjeel, Hassan Muhammad Mujeeb, Malik Moeena, Saleem Rabia, Tariq Zartasha, Zohaib Khurram, Javaid Maham, Malik Adnan Younas, Saleem Amna

机构信息

Radiology, Holy Family Hospital Rawalpindi, Rawalpindi, PAK.

Internal Medicine, Rawalpindi Medical University, Rawalpindi, PAK.

出版信息

Cureus. 2023 Oct 5;15(10):e46538. doi: 10.7759/cureus.46538. eCollection 2023 Oct.

Abstract

Introduction  Traditionally, different fetal variable measurements are used in ultrasound to assess fetal growth. Ultrasound can detect abnormal fetal growth. Gestational diabetes mellitus (GDM) is linked to higher fetal obesity as early as 20 weeks of pregnancy. The amount of fetal adipose tissue may be measured by measuring the thickness of the anterior abdominal wall. Measuring the thickness of the fetus's anterior abdominal wall (AAWT) is a straightforward procedure that may be performed alongside standard abdominal circumference measurements. Objectives  To check the diagnostic accuracy of fetal AAWT as an early sonographic sign for diagnosing GDM, keeping oral glucose tolerance test as the gold standard. Study design  This research was conducted using a cross-sectional analysis. Study place and duration The study was conducted in the Radiology Department at Rawalpindi Medical University and Allied Hospitals from July 10, 2019 to January 9, 2020. Materials and methods  Women between the ages of 18 and 45 who had a family history of type 2 diabetes and were at risk for developing GDM were recruited. Exclusions were made for diabetic women, those carrying multiples, and those with autoimmune diseases. The AAWT measurement of the fetus, which included the skin and subcutaneous tissue, was acquired using the traditional anterior cranial view, 2-3 cm lateral to cord insertion. Pregnant patients at risk for GDM underwent screening using an oral glucose tolerance test. Those exhibiting any two abnormal values were diagnosed with GDM. Results  The overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of fetal AAWT as an early sonographic sign for diagnosing GDM, with the oral glucose tolerance test as the gold standard, were 93.14%, 82.65%, 84.82%, 92.05%, and 88.0%, respectively. Conclusion  The study concludes that the diagnostic accuracy of fetal AAWT as an early sonographic indicator for identifying gestational diabetes is notably high.

摘要

引言 传统上,超声检查中使用不同的胎儿变量测量来评估胎儿生长情况。超声能够检测出胎儿生长异常。妊娠期糖尿病(GDM)早在怀孕20周时就与胎儿肥胖程度增加有关。胎儿脂肪组织的量可通过测量前腹壁厚度来测定。测量胎儿前腹壁(AAWT)厚度是一种简单的操作,可与标准腹围测量同时进行。

目的 以口服葡萄糖耐量试验作为金标准,检验胎儿AAWT作为诊断GDM的早期超声征象的诊断准确性。

研究设计 本研究采用横断面分析。

研究地点和时间 本研究于2019年7月10日至2020年1月9日在拉瓦尔品第医科大学及附属医院放射科进行。

材料和方法 招募年龄在18至45岁之间、有2型糖尿病家族史且有患GDM风险的女性。排除患有糖尿病的女性、怀有多胞胎的女性以及患有自身免疫性疾病的女性。使用传统的前颅视图,在脐带插入点外侧2 - 3厘米处获取包括皮肤和皮下组织的胎儿AAWT测量值。有GDM风险的孕妇接受口服葡萄糖耐量试验筛查。出现任何两项异常值的患者被诊断为GDM。

结果 以口服葡萄糖耐量试验作为金标准,胎儿AAWT作为诊断GDM的早期超声征象的总体敏感性、特异性、阳性预测值、阴性预测值和诊断准确性分别为93.14%、82.65%、84.82%、92.05%和88.0%。

结论 该研究得出结论,胎儿AAWT作为识别妊娠期糖尿病的早期超声指标,其诊断准确性显著较高。

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Fetal anterior abdominal wall thickness between gestational diabetes and normal pregnant women.
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