Aksoy Hüseyin, Aksoy Ulkü, Açmaz Gökhan, Tutuş Sadan
Department of Obstetrics and Gynecology, Kayseri Military Hospital, Kayseri, Turkey.
Diabetes Metab Res Rev. 2014 Oct;30(7):570-4. doi: 10.1002/dmrr.2511.
Patients with impaired 50-g oral glucose challenge test (OGCT) have not been investigated for fetal anterior abdominal wall thickness until now. We aimed to investigate patients with impaired 50-g OGCT, but not gestational diabetes and match them with healthy uneventful pregnant participants for anterior abdominal wall thickness, estimated fetal weight, fetal gender, biparietal diameter, femur length and abdominal circumference.
A total of 99 pregnant women between 26 and 28 weeks of gestation were enrolled in the study. These patients were divided into two groups according to their 50-g OGCT results. Fifty-one pregnant women with uncomplicated healthy singleton pregnancies constituted our control group, and 48 singleton pregnant women with impaired 50-g OGCT but normal 100-g oral glucose tolerance test constituted our study group.
We detected statistically significant high body mass index in impaired 50-g glucose test group. Biparietal diameter, femur length, abdominal circumference and estimated fetal weight values were not significantly different between groups; however, anterior abdominal wall thickness value was significantly width in impaired 50-g glucose test group. Moreover, there were no statistically significant differences between two groups for gender of fetuses.
Impaired 50-g glucose test in pregnancy is related not only to increased maternal body mass index but also to fetal fat distribution. Although fetal abdominal circumference measurement and estimated fetal weight were not different between study and control group, increased anterior abdominal wall thickness can be detected in impaired 50-g OGCT group.
迄今为止,尚未对50克口服葡萄糖耐量试验(OGCT)结果异常的患者进行胎儿前腹壁厚度的研究。我们旨在研究50克OGCT结果异常但无妊娠糖尿病的患者,并将其与健康、妊娠过程顺利的孕妇在胎儿前腹壁厚度、估计胎儿体重、胎儿性别、双顶径、股骨长度和腹围方面进行匹配。
本研究共纳入99例妊娠26至28周的孕妇。这些患者根据其50克OGCT结果分为两组。51例单胎妊娠、健康无并发症的孕妇组成我们的对照组,48例50克OGCT结果异常但100克口服葡萄糖耐量试验正常的单胎孕妇组成我们的研究组。
我们检测到50克葡萄糖试验异常组的体重指数在统计学上显著较高。两组之间的双顶径、股骨长度、腹围和估计胎儿体重值无显著差异;然而,50克葡萄糖试验异常组的前腹壁厚度值明显更宽。此外,两组胎儿性别之间无统计学显著差异。
孕期50克葡萄糖试验异常不仅与孕妇体重指数增加有关,还与胎儿脂肪分布有关。尽管研究组和对照组之间胎儿腹围测量值和估计胎儿体重无差异,但在50克OGCT异常组中可检测到前腹壁厚度增加。