Fundación Valle del Lili, Cali, CO.
Instituto de Cardiología J.F Cabral, Corrientes, AR.
Glob Heart. 2023 Nov 1;18(1):60. doi: 10.5334/gh.1272. eCollection 2023.
Socioeconomic factors contribute to a more severe impact of COVID-19 in Latin American and Caribbean (LA&C) countries than in developed countries. Patients with a severe or critical illness can develop respiratory and cardiovascular complications.
To describe a LA&C population with COVID-19 to provide information related to this disease, in-hospital cardiovascular complications, and in-hospital mortality.
The CARDIO COVID-19-20 Registry is an observational, multicenter, prospective, and hospital-based registry of patients with confirmed COVID-19 infection that required in-hospital treatment in LA&C. Enrollment of patients started on May 01, 2020, and ended on June 30, 2021.
The CARDIO COVID-19-20 Registry included 3260 patients from 44 institutions of 14 LA&C countries. 63.2% patients were male and median age was 61.0 years old. Most common comorbidities were overweight/obesity (49.7%), hypertension (49.0%), and diabetes mellitus (26.7%). Most frequent cardiovascular complications during hospitalization or reported at discharge were cardiac arrhythmia (9.1%), decompensated heart failure (8.5%), and pulmonary embolism (3.9%). The number of patients admitted to the Intensive Care Unit (ICU) was 1745 (53.5%), and median length of their stay at the ICU was 10.0 days. Support required in ICU included invasive mechanical ventilation (34.2%), vasopressors (27.6%), inotropics (10.3%), and vasodilators (3.7%). Rehospitalization after 30-day post discharge was 7.3%. In-hospital mortality and 30-day post discharge were 25.5% and 2.6%, respectively.
According to our findings, more than half of the LA&C population with COVID-19 assessed required management in ICU, with higher requirement of invasive mechanical ventilation and vasoactive support, resulting in a high in-hospital mortality and a considerable high 30-day post discharge rehospitalization and mortality.
社会经济因素导致拉丁美洲和加勒比（LA&C）国家 COVID-19 的影响比发达国家更为严重。患有严重或危重病的患者可能会出现呼吸和心血管并发症。
描述拉丁美洲和加勒比地区 COVID-19 人群，提供与该疾病相关的信息、住院期间心血管并发症和住院死亡率。
CARDIO COVID-19-20 登记处是一项观察性、多中心、前瞻性、以医院为基础的登记处，登记了在拉丁美洲和加勒比地区需要住院治疗的确诊 COVID-19 感染患者。患者招募于 2020 年 5 月 1 日开始，2021 年 6 月 30 日结束。
CARDIO COVID-19-20 登记处包括来自 14 个 LA&C 国家的 44 个机构的 3260 名患者。63.2%的患者为男性，中位年龄为 61.0 岁。最常见的合并症是超重/肥胖（49.7%）、高血压（49.0%）和糖尿病（26.7%）。住院期间或出院时报告的最常见心血管并发症是心律失常（9.1%）、心力衰竭失代偿（8.5%）和肺栓塞（3.9%）。需要入住重症监护病房（ICU）的患者人数为 1745 人（53.5%），他们在 ICU 的中位住院时间为 10.0 天。在 ICU 中需要的支持包括有创机械通气（34.2%）、血管加压药（27.6%）、正性肌力药（10.3%）和血管扩张剂（3.7%）。出院后 30 天内再入院率为 7.3%。住院死亡率和出院后 30 天死亡率分别为 25.5%和 2.6%。
根据我们的发现，评估的拉丁美洲和加勒比地区 COVID-19 人群中超过一半需要在 ICU 进行管理，需要更多的有创机械通气和血管活性支持，导致住院死亡率高，出院后 30 天内再住院和死亡率高。
