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报告 COVID-19 患者的生化血液值:一项回顾性研究。

Reporting of biochemical blood values in COVID-19 patients: A retrospective study.

机构信息

Şehit Prof. Dr. İlhan Varank Sancaktepe Training and Research Hospital, Department of Pathology, Emek, İstanbul, Turkey.

Sultanbeyli State Hospital, Department of Emergency, Battalgazi, Sultanbeyli, İstanbul, Turkey.

出版信息

Medicine (Baltimore). 2023 Nov 3;102(44):e35833. doi: 10.1097/MD.0000000000035833.

DOI:10.1097/MD.0000000000035833
PMID:37933044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10627609/
Abstract

BACKGROUND

This study aimed to investigate the impact of biochemical blood parameters on the progression of coronavirus disease (COVID-19). This retrospective study analyzed the clinical characteristics and biochemical test parameters of 352 COVID-19 patients treated at Malatya Training and Research Hospital in Turkey between March 3, 2021, and February 28, 2022.

METHODS

The methodological approach of our study included specific analyses and examinations to assess the effect of biochemical blood values on disease progression in COVID-19 patients. To achieve this aim, blood samples were collected from patients and various biochemical tests were performed. The data obtained were evaluated using statistical analyses to examine the relationship between these specific biochemical blood values and the severity of COVID-19.

RESULTS

High glucose, urea, alkaline phosphatase and lactate dehydrogenase levels and low albumin and potassium levels were associated with a more severe disease course. The results showed a significant link between certain biochemical blood values and the severity of COVID-19. These findings suggest that these markers may serve as valuable clinical indicators for predicting the disease progression and severity.

CONCLUSION

This study demonstrates the importance of monitoring and analyzing biochemical blood values as essential tools for assessing the severity and progression of COVID-19. The identified markers provide valuable information regarding the prognosis of the disease and may help healthcare professionals make informed decisions regarding patient care.

摘要

背景

本研究旨在探讨生化血液参数对冠状病毒病(COVID-19)进展的影响。这项回顾性研究分析了 2021 年 3 月 3 日至 2022 年 2 月 28 日在土耳其马拉蒂亚培训和研究医院治疗的 352 例 COVID-19 患者的临床特征和生化检验参数。

方法

我们的研究方法包括特定的分析和检查,以评估生化血液值对 COVID-19 患者疾病进展的影响。为了实现这一目标,从患者身上采集血液样本,并进行各种生化测试。使用统计分析评估获得的数据,以检查这些特定生化血液值与 COVID-19 严重程度之间的关系。

结果

高血糖、尿素、碱性磷酸酶和乳酸脱氢酶水平以及低白蛋白和钾水平与更严重的疾病过程相关。结果表明,某些生化血液值与 COVID-19 的严重程度之间存在显著关联。这些发现表明,这些标志物可能是预测疾病进展和严重程度的有价值的临床指标。

结论

本研究表明,监测和分析生化血液值是评估 COVID-19 严重程度和进展的重要工具。确定的标志物提供了有关疾病预后的有价值信息,并可能有助于医疗保健专业人员就患者护理做出明智决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ca/10627609/ebea5a5e9b2d/medi-102-e35833-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ca/10627609/72ec7bdfde74/medi-102-e35833-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ca/10627609/ebea5a5e9b2d/medi-102-e35833-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ca/10627609/72ec7bdfde74/medi-102-e35833-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ca/10627609/ebea5a5e9b2d/medi-102-e35833-g002.jpg

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