关于变形虫、军团菌与人类之间关系的当前观点。

Current views on the relationships between amoebae, legionellae and man.

作者信息

Rowbotham T J

出版信息

Isr J Med Sci. 1986 Sep;22(9):678-89.

Abstract

Amoebae are natural hosts for legionellae. The significance of this with regard to the multiplication of legionellae in the environment, the protection of legionellae from biocides, and the epidemiology of Legionnaires' Disease and Pontiac fever are discussed. A vesicle, or small amoeba, containing many legionellae is suggested as the main infective particle for man. We believe Pontiac fever can be explained as involving hypersensitivity to acanthamoebae, and comment on the lack of phages for legionellae. Legionella-like amoebal pathogen 1 (LLAP-1) was isolated, and probably belongs to a new species of Legionella. Further amoebal hosts for legionellae were found.

摘要

变形虫是军团菌的天然宿主。本文讨论了这一现象在军团菌在环境中繁殖、军团菌免受杀菌剂影响以及军团病和庞蒂亚克热流行病学方面的意义。一个含有许多军团菌的囊泡或小变形虫被认为是人类的主要感染颗粒。我们认为庞蒂亚克热可以解释为对棘阿米巴的超敏反应，并对军团菌缺乏噬菌体的情况进行了评论。分离出了军团菌样阿米巴病原体1（LLAP-1），它可能属于军团菌的一个新物种。还发现了军团菌的其他变形虫宿主。