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脉冲场消融的前景与面临的挑战。

The promise of pulsed field ablation and the challenges ahead.

作者信息

Iyengar Shruti Krishna, Iyengar Sumedh, Srivathsan Komandoor

机构信息

The Division of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, AZ, United States.

出版信息

Front Cardiovasc Med. 2023 Oct 23;10:1235317. doi: 10.3389/fcvm.2023.1235317. eCollection 2023.

Abstract

For many years, guidelines have suggested thermal ablation for the treatment of atrial fibrillation. Thermal ablation involves the destruction of tissue, leading to multiple complications. This ablation technique has been tried and tested, however, newer techniques are being investigated in order to avoid these complications. Pulsed field ablation, a nonthermal method of tissue ablation, is being explored as a more safe and efficient way to treat atrial fibrillation. This mini review aims to highlight the mechanisms of pulsed field ablation, its history and evolution, previous studies showing its efficacy, its major challenges and pitfalls, and future advancements to overcome these challenges. This method of ablation could potentially revolutionize the treatment of atrial fibrillation and prevent recurrences, thereby making it easier for the physicians and patients involved.

摘要

多年来,指南一直建议采用热消融术治疗心房颤动。热消融涉及组织破坏,会引发多种并发症。这种消融技术已经经过试验和验证,然而,为了避免这些并发症,人们正在研究更新的技术。脉冲场消融作为一种非热组织消融方法,正被探索为一种更安全、有效的治疗心房颤动的方式。本综述旨在突出脉冲场消融的机制、其历史与发展、表明其疗效的既往研究、其主要挑战与陷阱,以及克服这些挑战的未来进展。这种消融方法有可能彻底改变心房颤动的治疗方式并预防复发,从而让相关医生和患者的治疗过程更加轻松。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0651/10627215/438a94b49509/fcvm-10-1235317-g001.jpg

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