Department of Urology, T.C. Ministry of Health Karabuk Training and Research Hospital, Karabuk, Turkey.
Urol Int. 2024;108(1):60-64. doi: 10.1159/000535033. Epub 2023 Nov 8.
To compare the effects of three techniques: biopsy needle disinfection with 10% formalin solution, povidone-iodine rectal cleaning, and the use of both methods to decrease hospitalization due to infectious complications after transrectal prostate biopsy.
A total of 827 patients were divided into 3 groups. Group 1 patient data were analyzed retrospectively, while patients of groups 2 and 3 were followed up prospectively. Group 1 included 361 patients who underwent biopsy needle disinfection with a 10% formalin solution. Group 2 included 235 patients who underwent biopsy needle disinfection and povidone-iodine rectal cleaning. Group 3 included 231 patients who underwent povidone-iodine rectal cleaning only. The outcome scale was the number of patients hospitalized for biopsy-related infection 30 days after the date of transrectal prostate biopsy.
The hospitalization rates due to biopsy-related infectious complications were 3.0%, 0%, and 1.7% in groups 1, 2, and 3, respectively. The only statistically significant difference was found between groups 1 and 2.
Biopsy needle disinfection and rectal cleaning with povidone-iodine seem to have greater potential to reduce infectious complications when applied together. Further prospective studies are required to confirm these findings.
比较三种技术的效果：10%福尔马林溶液消毒活检针、聚维酮碘直肠清洁，以及同时使用这两种方法降低经直肠前列腺活检后因感染性并发症而住院的几率。
共 827 名患者分为 3 组。第 1 组患者数据进行回顾性分析，第 2 组和第 3 组患者则前瞻性随访。第 1 组包括 361 名接受 10%福尔马林溶液消毒活检针的患者。第 2 组包括 235 名接受活检针消毒和聚维酮碘直肠清洁的患者。第 3 组包括仅接受聚维酮碘直肠清洁的 231 名患者。结局指标为经直肠前列腺活检后 30 天内因活检相关感染而住院的患者人数。
第 1、2、3 组因活检相关感染性并发症而住院的发生率分别为 3.0%、0%和 1.7%。仅第 1 组和第 2 组之间存在统计学显著差异。
活检针消毒和聚维酮碘直肠清洁联合应用似乎更有潜力降低感染性并发症。需要进一步的前瞻性研究来证实这些发现。
