Department of Neurobiology, University of California, Los Angeles, California 90095
Department of Psychology, University of California, Los Angeles, Los Angeles, California 90095.
J Neurosci. 2023 Nov 8;43(45):7565-7574. doi: 10.1523/JNEUROSCI.1430-23.2023.
The ability to store information about the past to dynamically predict and prepare for the future is among the most fundamental tasks the brain performs. To date, the problems of understanding how the brain stores and organizes information about the past (memory) and how the brain represents and processes temporal information for adaptive behavior have generally been studied as distinct cognitive functions. This Symposium explores the inherent link between memory and temporal cognition, as well as the potential shared neural mechanisms between them. We suggest that working memory and implicit timing are interconnected and may share overlapping neural mechanisms. Additionally, we explore how temporal structure is encoded in associative and episodic memory and, conversely, the influences of episodic memory on subsequent temporal anticipation and the perception of time. We suggest that neural sequences provide a general computational motif that contributes to timing and working memory, as well as the spatiotemporal coding and recall of episodes.
储存过去信息以动态预测和准备未来的能力是大脑执行的最基本任务之一。迄今为止，理解大脑如何存储和组织过去的信息（记忆）以及大脑如何代表和处理适应行为的时间信息的问题通常被视为不同的认知功能进行研究。本次研讨会探讨了记忆和时间认知之间的内在联系，以及它们之间潜在的共享神经机制。我们认为，工作记忆和内隐时间具有关联性，可能共享重叠的神经机制。此外，我们还探讨了时间结构如何在联想记忆和情景记忆中被编码，以及情景记忆对后续时间预期和时间感知的影响。我们认为，神经序列提供了一种通用的计算模式，有助于时间和工作记忆，以及情景的时空编码和回忆。
