[非那西泮对大鼠乙醇需求量的影响]
[Effect of phenazepam on the ethanol demand of rats].
作者信息
Zakusov V V, Liubimov B I, Iavorskiĭ A N, Fokin V I
出版信息
Biull Eksp Biol Med. 1979 Jul;88(7):32-5.
PMID:37944
Abstract
The new Soviet tranquilizer phenazepam given to rats intraperitoneally at a dose of 1 mg/kg daily was shown to be capable of suppressing ethanol addiction produced by 2-month intake of 5% ethanolic solution as the only source of liquid. The mechanism of this effect is likely to be related to the changes in the activity of the neurosecretory centers of the hypothalamus. The phenazepam in the treatment of chronic alcoholism.
摘要
给大鼠腹腔注射新的苏联镇静剂非那西泮，剂量为每日1毫克/千克，结果表明它能够抑制因连续两个月将5%乙醇溶液作为唯一液体来源而产生的乙醇成瘾。这种作用机制可能与下丘脑神经分泌中心活动的变化有关。非那西泮可用于治疗慢性酒精中毒。
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