Chen Yuan, Liu Meiqi, Wen Jinli, Yang Zijie, Li Guohui, Cao Ying, Sun Lili, Ren Xiaoliang
School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Chin Med. 2023 Nov 10;18(1):148. doi: 10.1186/s13020-023-00857-y.
Panax japonicus C.A. Meyer (Zhujieshen) is widely used in traditional medicine as a tonic hemostatic and anti-inflammatory agent in China, Japan, and Korea. Furthermore, it is used as an important substitute for ginseng roots by minority ethnic groups in China. The purpose of this review is to summarize the latest research on Zhujieshen in recent years, aiming at providing a systematic overview of the current knowledge, and perspectives for future research and exploitation.
This review examines the research advances in botanical profile, phytochemicals, pharmacology, pharmacokinetics, and authentication of Zhujieshen. Various compounds have been reported as active components, mainly including saponins, volatile oils, and polysaccharides. Pharmacological investigations have demonstrated that Zhujieshen is an important herb with significant bioactivities, such as anti-inflammatory, hepato-protective, cardio-protective, neuro-protective, anti-tumor, anti-oxidant, anti-thrombotic and immunomodulatory activities.
Currently, research on Zhujieshen is in the preliminary stages, and further research is required to understand the active compounds present and mechanisms of action. We hope that this comprehensive review of Zhujieshen will serve as a background for future research and exploitation.
竹节参（Panax japonicus C.A. Meyer）在中国、日本和韩国作为滋补止血和抗炎剂被广泛应用于传统医学。此外，它还被中国少数民族用作人参根的重要替代品。本综述的目的是总结近年来竹节参的最新研究，旨在提供对现有知识的系统概述以及未来研究和开发的前景。
本综述考察了竹节参在植物形态、植物化学、药理学、药代动力学和鉴定方面的研究进展。已报道多种化合物为活性成分，主要包括皂苷、挥发油和多糖。药理学研究表明，竹节参是一种具有重要生物活性的草药，具有抗炎、保肝、心脏保护、神经保护、抗肿瘤、抗氧化、抗血栓和免疫调节等活性。
目前，竹节参的研究尚处于初步阶段，需要进一步研究以了解其所含活性化合物及其作用机制。我们希望对竹节参的这一全面综述能为未来的研究和开发提供背景参考。
