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睡眠障碍对 BDD 症状和治疗反应的影响。

Impact of sleep disruption on BDD symptoms and treatment response.

机构信息

Massachusetts General Hospital, United States of America; Harvard Medical School, United States of America.

Massachusetts General Hospital, United States of America.

出版信息

J Affect Disord. 2024 Feb 1;346:206-213. doi: 10.1016/j.jad.2023.11.028. Epub 2023 Nov 11.

Abstract

BACKGROUND

Body dysmorphic disorder (BDD) is severe, undertreated, and relatively common. Although gold-standard cognitive behavioral therapy (CBT) for BDD has strong empirical support, a significant number of patients do not respond. More work is needed to understand BDD's etiology and modifiable barriers to treatment response. Given its high prevalence and impact on the development, maintenance, and treatment of related, frequently comorbid disorders, sleep disruption is a compelling, but not-yet studied factor.

METHODS

Data were drawn from a randomized controlled trial of guided smartphone app-based CBT for BDD. Included participants were offered 12-weeks of treatment, immediately (n = 40) or after a 12-week waitlist (n = 37). Sleep disruption and BDD symptom severity were assessed at baseline, week-6, and week-12.

RESULTS

Hypotheses and analysis plan were pre-registered. Two-thirds of patients reported significant insomnia symptoms at baseline. Baseline severity of sleep disruption and BDD symptoms were not related (r = 0.02). Pre-treatment sleep disruption did not predict BDD symptom reduction across treatment, nor did early sleep improvements predict greater BDD symptom improvement. Early BDD symptom improvement also did not predict later improvements in sleep.

LIMITATIONS

Limitations include the small sample, restricted ranges of BDD symptom severity and treatment response, and few metrics of sleep disruption.

CONCLUSIONS

Although insomnia was disproportionately high in this sample and both BDD symptoms and sleep improved in treatment, results suggest sleep and BDD symptoms may function largely independent of one another. More work is encouraged to replicate and better understand findings as well as potential challenges and benefits of addressing sleep in BDD.

摘要

背景

躯体变形障碍(BDD)是一种严重的、治疗不足且相对常见的疾病。尽管针对 BDD 的黄金标准认知行为疗法(CBT)具有强有力的实证支持,但仍有相当数量的患者没有得到回应。为了更好地了解 BDD 的病因和治疗反应的可改变障碍,还需要开展更多的工作。鉴于睡眠障碍的高发病率及其对相关、经常共病障碍的发展、维持和治疗的影响,它是一个引人关注但尚未得到研究的因素。

方法

本研究的数据来自于一项针对 BDD 的基于智能手机应用的引导式 CBT 的随机对照试验。纳入的参与者提供了 12 周的治疗,立即治疗(n=40)或等待 12 周后治疗(n=37)。在基线、第 6 周和第 12 周评估睡眠障碍和 BDD 症状严重程度。

结果

假设和分析计划是预先注册的。三分之二的患者在基线时报告有严重的失眠症状。睡眠障碍和 BDD 症状的基线严重程度没有相关性(r=0.02)。治疗前的睡眠障碍并不能预测 BDD 症状的减轻,早期的睡眠改善也不能预测 BDD 症状的更大改善。早期 BDD 症状的改善也不能预测随后睡眠的改善。

局限性

局限性包括样本量小、BDD 症状严重程度和治疗反应的范围有限,以及睡眠障碍的指标较少。

结论

尽管在这个样本中失眠的比例过高,而且 BDD 症状和睡眠在治疗中都有所改善,但结果表明睡眠和 BDD 症状可能在很大程度上是相互独立的。鼓励开展更多的工作来复制和更好地理解这些发现,以及在 BDD 中解决睡眠问题的潜在挑战和益处。

相似文献

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Impact of sleep disruption on BDD symptoms and treatment response.睡眠障碍对 BDD 症状和治疗反应的影响。
J Affect Disord. 2024 Feb 1;346:206-213. doi: 10.1016/j.jad.2023.11.028. Epub 2023 Nov 11.

本文引用的文献

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Sleep disturbance and psychiatric disorders.睡眠障碍与精神疾病。
Lancet Psychiatry. 2020 Jul;7(7):628-637. doi: 10.1016/S2215-0366(20)30136-X.

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