Department of Thoracic Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China (mainland).
Department of Gynecology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China (mainland).
Med Sci Monit. 2023 Nov 13;29:e941577. doi: 10.12659/MSM.941577.
BACKGROUND The study aimed to compare the patient-reported outcomes in patients who underwent early vs conventional feeding after thoracoscopic lung cancer resection. MATERIAL AND METHODS The study enrolled 211 patients who underwent thoracoscopic lung cancer resection at a tertiary hospital between July 2021 and July 2022. Patients were randomly assigned to the conventional group or the early feeding group. There were 106 patients in the early feeding group and 105 patients in the conventional group. The conventional group received water 4 h after extubation and liquid/semi-liquid food 6 h after extubation. In contrast, the early feeding group received water 1 h after extubation and liquid/semi-liquid food 2 h after extubation. The primary outcomes were the degree of hunger, thirst, nausea, and vomiting. The secondary outcomes were postoperative complications, duration of hospital stay, and chest tube drainage. RESULTS No differences were found between the 2 groups in the degrees of postoperative nausea, vomiting, or pain after extubation for 1, 2, 4, and 8 h. Postoperative complications, duration of chest tube drainage, and duration of hospital stay were also similar (P=0.567, P=0.783, P=0.696). However, the hunger and thirst scores after extubation for 2 h and 4 h decreased and were lower in the early feeding group (both P<0.001). No patients developed choking, postoperative aspiration, gastrointestinal obstruction, or other complications. CONCLUSIONS Early oral feeding after thoracoscopic lung cancer resection is safe and can increase patient comfort postoperatively.
本研究旨在比较胸腔镜肺癌切除术后早期与常规喂养的患者报告结局。
本研究纳入了 2021 年 7 月至 2022 年 7 月在一家三级医院接受胸腔镜肺癌切除术的 211 名患者。患者被随机分配至常规组或早期喂养组。早期喂养组 106 例,常规组 105 例。常规组在拔管后 4 小时给予水,拔管后 6 小时给予液体/半液体食物。相比之下,早期喂养组在拔管后 1 小时给予水,拔管后 2 小时给予液体/半液体食物。主要结局为饥饿、口渴、恶心和呕吐程度。次要结局为术后并发症、住院时间和胸腔引流管引流量。
两组患者在拔管后 1、2、4 和 8 小时的术后恶心、呕吐或疼痛程度无差异。术后并发症、胸腔引流管引流量和住院时间也相似(P=0.567,P=0.783,P=0.696)。然而,拔管后 2 小时和 4 小时的饥饿和口渴评分降低,且早期喂养组的评分更低(均 P<0.001)。无患者发生呛咳、术后吸入、胃肠道梗阻或其他并发症。
胸腔镜肺癌切除术后早期口服喂养安全,并可增加术后患者舒适度。