Topchiĭ I I
Kardiologiia. 1986 Oct;26(10):32-5.
Patterns of red blood cell hemostasis and microcirculation changes are analysed in 115 chronic coronary patients in the course of purposeful medication and at extracorporeal carbohemoperfusion. Differences in the mechanisms of action of trental, phosphaden and essentiale are identified by means of television capillaroscopy, termography, scanning electron microscopy; the mechanism of the antianginal effect of extracorporeal carbohemoperfusion is specified. A considerable disaggregating effect associated with trental and phosphaden, as well as an essentiale-associated improvement in red blood cell morphology and membrane permeability were demonstrated. Extracorporeal carbohemoperfusion is followed by an improvement of red blood cell hemostasis and microcirculation characteristics and a decrease in plasma lipoproteins.
对115例慢性冠心病患者在有针对性的药物治疗过程中及体外碳氧血红蛋白灌注时的红细胞止血模式和微循环变化进行了分析。通过电视毛细血管镜检查、热像图检查、扫描电子显微镜确定了曲克芦丁、磷酸腺苷和肝得健的作用机制差异；明确了体外碳氧血红蛋白灌注抗心绞痛作用的机制。证实了曲克芦丁和磷酸腺苷具有显著的解聚作用，以及肝得健对红细胞形态和膜通透性的改善作用。体外碳氧血红蛋白灌注后，红细胞止血和微循环特征得到改善，血浆脂蛋白降低。
