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[血液吸附对稳定型心绞痛患者微循环、体液自身免疫及脂质过氧化的影响]

[Effect of hemosorption on microcirculation, humoral autoimmunity and lipid peroxidation in patients with stable angina pectoris].

作者信息

Atroshchenko E S, Shagusultanov E R, Karpova I S, Cheshchevik A B, Kalinina L M

出版信息

Kardiologiia. 1992 May;32(5):29-31.

PMID:1405255
Abstract

Microhemo- and lymphocirculation, capillary permeability, humoral autoimmunity and lipid peroxidation were determined in 46 patients with Functional Classes III-IV stable angina concurrent with multiple atherosclerotic coronary lesions 24 hours following the second hemosorption session. The clinical efficiency of hemosorption was observed in 47.8% of patients with stenotic coronary atherosclerosis refractory to antianginal therapy. In this group of patients, hemosorption led to accelerated microcirculation, increased microcirculatory reserve potentials and decreased microvascular resistance at rest and in reactive postischemic hyperemia. In patients with abnormal humoral autoimmunity and lipid peroxidation, hemosorption resulted in their hormalization.

摘要

在46例患有功能性III-IV级稳定型心绞痛并伴有多处动脉粥样硬化性冠状动脉病变的患者中,在第二次血液吸附治疗24小时后测定了微血循环和淋巴循环、毛细血管通透性、体液自身免疫和脂质过氧化情况。在47.8%对抗心绞痛治疗无效的狭窄性冠状动脉粥样硬化患者中观察到了血液吸附的临床疗效。在这组患者中,血液吸附导致微循环加速,微循环储备潜能增加,静息时和缺血后反应性充血时的微血管阻力降低。在体液自身免疫和脂质过氧化异常的患者中,血液吸附使其恢复正常。

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1
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Kardiologiia. 1992 May;32(5):29-31.
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