Jostarndt L, Nitsche D, Löhnert M, Albers U, Hamelmann H
Langenbecks Arch Chir. 1986;368(2):97-103. doi: 10.1007/BF01273848.
In a prospective consecutive study of 40 patients with anal fissure we analysed the anal sphincter function at rest and rectal distension. Healthy persons with comparable age and sex distribution were controls. The anal pressures were registered with thin water perfused catheters (2 ml/min). Our patients with anal fissure showed significant elevation of anal pressures at rest along the whole length of anal canal. During rectal distension only the distal part of anal sphincter (up to a level of 2 cm from the anocutaneous line) showed a spasm with reduced relaxation. Our results are useful for operative therapy, since lateral internal sphincterotomy corresponds very well to functional pathomechanism of anal fissure.
在一项对40例肛裂患者的前瞻性连续研究中，我们分析了静息状态及直肠扩张时的肛门括约肌功能。年龄和性别分布与之匹配的健康人作为对照。使用细的水灌注导管（2毫升/分钟）记录肛门压力。我们的肛裂患者在肛管全长静息时肛门压力显著升高。在直肠扩张时，仅肛门括约肌的远端部分（距肛门皮肤线2厘米以内）出现痉挛且松弛减弱。我们的结果对手术治疗有帮助，因为侧方内括约肌切开术与肛裂的功能病理机制非常吻合。
