McConnell M R, Foster B D, Davis D P, Kat B, Blair J G, Long R A, Steed M M
Microbios. 1986;48(196-197):135-58.
A spontaneously derived mutant of the smooth bacterial strain, Salmonella anatum A1, specifically blocks the DNA ejection function of bacteriophage E15 during infection. The mutant, AE15R-5, exhibits mucoid colony morphology but no evidence of colanic acid biosynthesis. It is resistant not only to bacteriophage E15, but also to all other smooth- and rough-specific phages which have been tested. Chemical, immunological and gel electrophoretic analyses indicate that its lipopolysaccharide (LPS) molecules fall into two categories: they are either highly truncated (probably heptoseless) or extremely large (complete LPS molecules with O-polysaccharides containing 80 or more repeat units). The antibiotic resistance pattern of AE15R-5 is roughly intermediate between that of a known heptoseless mutant, S. anatum MG4, and that of the parent strain, S. anatum A-1.
光滑型细菌菌株鸭沙门氏菌A1的一个自发衍生突变体，在感染过程中特异性地阻断噬菌体E15的DNA喷射功能。该突变体AE15R - 5表现出黏液状菌落形态，但没有证据表明其合成结肠酸。它不仅对噬菌体E15具有抗性，而且对所有其他已测试的光滑型和粗糙型特异性噬菌体也具有抗性。化学、免疫学和凝胶电泳分析表明，其脂多糖（LPS）分子分为两类：它们要么高度截短（可能不含庚糖），要么极大（带有含80个或更多重复单元的O - 多糖的完整LPS分子）。AE15R - 5的抗生素抗性模式大致介于已知的不含庚糖突变体鸭沙门氏菌MG4和亲本菌株鸭沙门氏菌A - 1之间。
