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饮用水研究领域的视野局限——是时候实施非靶向分析了吗?

Tunnel vision in the drinking water research field - Time for non-targeted analysis implementation?

作者信息

Kutil Zsofia, Novotna Katerina, Cermakova Lenka, Pivokonsky Martin

机构信息

Institute of Hydrodynamics of the Czech Academy of Sciences, Pod Patankou 30/5, 160 00 Prague 6, Czech Republic.

Institute of Hydrodynamics of the Czech Academy of Sciences, Pod Patankou 30/5, 160 00 Prague 6, Czech Republic.

出版信息

Sci Total Environ. 2024 Jan 15;908:168367. doi: 10.1016/j.scitotenv.2023.168367. Epub 2023 Nov 12.

DOI:10.1016/j.scitotenv.2023.168367
PMID:37963540
Abstract

A plethora of compounds can reach our drinking water and possibly affect human health. Still, mostly notorious pollutants like pesticides and disinfection by-products are monitored and regulated. With the increasing availability of high-resolution mass spectrometers (HRMS), non-targeted analyses of environmental samples have become possible. Pilot studies demonstrating the applicability of this approach in the drinking water research field were published. We would like to highlight these studies and appeal to researchers focused on water quality to better exploit the potential of HRMS instruments and broaden the scale of studied pollutants. In addition, the data and experience should be further shared, and the quality standard for the analytical procedures should be set. With advanced knowledge of compounds reaching the drinking water, potential threats would be revealed, and the comprehensive results on water pollution might also act as impulses for associated research branches, including toxicity assessment or development of water treatment technologies, and/or for policy-making.

摘要

大量化合物可能进入我们的饮用水并可能影响人类健康。尽管如此,目前主要监测和监管的是农药和消毒副产物等臭名昭著的污染物。随着高分辨率质谱仪(HRMS)的日益普及,对环境样品进行非靶向分析已成为可能。已发表了一些试点研究,证明了这种方法在饮用水研究领域的适用性。我们想强调这些研究,并呼吁专注于水质的研究人员更好地利用HRMS仪器的潜力,扩大所研究污染物的范围。此外,应进一步共享数据和经验,并制定分析程序的质量标准。凭借对进入饮用水的化合物的深入了解,潜在威胁将被揭示,水污染的综合结果也可能推动相关研究分支,包括毒性评估或水处理技术的开发,和/或为政策制定提供动力。

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