Department of Head, Neck and Sense Organs, School of Dentistry, Catholic University of Sacred Heart, Rome, Italy.
Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
BMC Oral Health. 2023 Nov 14;23(1):862. doi: 10.1186/s12903-023-03485-y.
Minor salivary glands can be found in the ventral and anterior part of the tongue; these glands can rarely develop mucoceles that, due to their rarity and their unusual clinical appearance, may present an interesting differential diagnosis. Mucoceles appear as an exophytic, sometimes pedunculated, lesion, which is a feature that is due to the absence of a capsule; thus, the glands are right beneath the mucosa and over the muscle tissue. The aim of this article is to retrospectively present and discuss the anatomy, pathology, clinical features and therapy of several cases of Blandin-Nunh mucoceles collected from two different institutions.
A retrospective case review was carried out in two university institutions, retrieving all cases of tongue mucoceles from 1999 to today. Two oral pathologists reviewed all the slides, confirming the diagnosis. Demographic data of the patient, anatomic location and clinical appearance were retrieved from clinical charts, together with the type of surgical procedure and possible relapses.
A total of 240 cases of tongue mucoceles were gathered from the archives: the mean age was 22 years (DS = 14,7; Range 2-83), 126 were females (52,5%, mean age 22,7 years, DS = 16,5; Range 2-83), and 114 were males (47,5%, mean age 20,9 years, DS = 12,4; Range 3-73); in all cases, a history of trauma was reported. The ventral surface was the most frequent location (224 cases - 93,3%), and in the great majority (235 cases - 97,9%), pathology revealed mucous spillage with a wall formed by fibrous connective and granulation tissue with no epithelium lining the cavity. Superficial mucocele and sclerosing sialoadenitis were the more frequent pathological variants (21 cases - 8,8%). All lesions were treated with excision and enucleation of the servicing gland. The healing was uneventful in all cases, but there were four recurrences and two cases of sensory paraesthesia of the border of the tongue, all in males, except one case of paraesthesia in a female.
Tongue mucoceles must be differentiated from many benign and malignant lesions. For this reason, surgical removal of the lesion and of the associated gland with a pathological exam is mandatory. In fact, the anatomical location of the glands and the possible pathological variants must be considered to reach a correct diagnosis and diminish possible relapses.
CE-Muc_Ton_3/2023.
小唾液腺位于舌的腹侧和前部；这些腺体很少会发展成黏液囊肿，由于其罕见性和异常的临床表现，可能会呈现出有趣的鉴别诊断。黏液囊肿表现为外生性的，有时带蒂的病变，这是由于缺乏包膜所致；因此，腺体位于黏膜下方和肌肉组织之上。本文的目的是回顾性地介绍和讨论从两个不同机构收集的几例 Blandin-Nunh 黏液囊肿的解剖、病理、临床特征和治疗方法。
在两个大学机构进行了回顾性病例回顾，从 1999 年至今检索了所有舌黏液囊肿的病例。两名口腔病理学家对所有切片进行了复查，以确认诊断。从临床病历中检索了患者的人口统计学数据、解剖位置和临床外观，以及手术类型和可能的复发情况。
从档案中收集了 240 例舌黏液囊肿：平均年龄为 22 岁（DS=14.7；范围 2-83），126 例为女性（52.5%，平均年龄 22.7 岁，DS=16.5；范围 2-83），114 例为男性（47.5%，平均年龄 20.9 岁，DS=12.4；范围 3-73）；在所有病例中，均有创伤史。腹侧表面是最常见的部位（224 例 - 93.3%），在绝大多数（235 例 - 97.9%）中，病理学显示黏液溢出，壁由纤维结缔组织和肉芽组织形成，腔无上皮衬里。浅表黏液囊肿和硬化性唾液腺炎是更常见的病理变异（21 例 - 8.8%）。所有病变均采用切除和服务腺体的摘除术治疗。所有病例均愈合良好，但有 4 例复发和 2 例舌缘感觉性麻木，均为男性，除 1 例外为女性。
舌黏液囊肿必须与许多良性和恶性病变相鉴别。因此，必须进行病变和相关腺体的手术切除，并进行病理检查。事实上，必须考虑腺体的解剖位置和可能的病理变异，以做出正确的诊断并减少可能的复发。
CE-Muc_Ton_3/2023。
