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病理检查结果与正电子发射断层扫描/计算机断层扫描中氟-18氟脱氧葡萄糖蓄积情况的比较:1例复发性多软骨炎病例

Comparison of pathological findings and accumulation of fluorin-18 fluorodeoxyglucose on positron emission tomography/computed tomography: A case of relapsing polychondritis.

作者信息

Tokuyasu Hirokazu, Watanabe Haruka, Sueda Yuriko, Sakai Hiromitsu, Omura-Tanaka Natsumi, Nakajima Kenichirou, Nakamatsu Satoru, Esumi Chika, Yamasaki Akira

机构信息

Department of Respiratory Medicine, Matsue Red Cross Hospital, Shimane, Japan.

Department of Otolaryngology, Matsue Red Cross Hospital, Shimane, Japan.

出版信息

Respir Med Case Rep. 2023 Oct 21;46:101937. doi: 10.1016/j.rmcr.2023.101937. eCollection 2023.

DOI:10.1016/j.rmcr.2023.101937
PMID:37965629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10641241/
Abstract

A 70-year-old woman with a hoarse voice and dry cough was referred to our hospital. Positron emission tomography/computed tomography showed abnormal accumulation of fluorine-18 fluorodeoxyglucose (FDG) at the nasal septum, larynx, trachea, bronchus, and costal cartilages. The maximum standard uptake values of FDG accumulation in the nasal septum and costal cartilage were similar. Biopsies of the nasal septum and costal cartilage were performed. The patient was diagnosed with relapsing polychondritis (RP) based on the clinical features and pathological findings. Histopathological examination revealed progressive initial RP findings. The disease progression was different, even with the same FDG accumulation.

摘要

一名声音嘶哑、干咳的70岁女性被转诊至我院。正电子发射断层扫描/计算机断层扫描显示,氟-18氟脱氧葡萄糖(FDG)在鼻中隔、喉、气管、支气管和肋软骨处异常聚集。鼻中隔和肋软骨中FDG聚集的最大标准摄取值相似。对鼻中隔和肋软骨进行了活检。根据临床特征和病理结果,该患者被诊断为复发性多软骨炎(RP)。组织病理学检查显示为进展期原发性RP表现。即使FDG聚集情况相同,疾病进展也有所不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/89e018dff9a4/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/c46ab5102f68/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/fa7bebb86d01/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/babd30d4cd75/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/89e018dff9a4/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/c46ab5102f68/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/fa7bebb86d01/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/babd30d4cd75/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/10641241/89e018dff9a4/gr4.jpg

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本文引用的文献

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Treatment of relapsing polychondritis: a systematic review.复发性多软骨炎的治疗:系统评价。
Clin Exp Rheumatol. 2022 May;40 Suppl 134(5):81-85. doi: 10.55563/clinexprheumatol/h9gq1o. Epub 2022 Jan 28.
2
Is F-FDG PET/CT useful for diagnosing relapsing polychondritis with airway involvement and monitoring response to steroid-based therapy?F-FDG PET/CT 对诊断气道受累的复发性多软骨炎及监测基于类固醇的治疗反应是否有用?
Arthritis Res Ther. 2019 Dec 12;21(1):282. doi: 10.1186/s13075-019-2083-8.
3
Efficacy and safety of biologics in relapsing polychondritis: a French national multicentre study.
生物制剂治疗复发性多软骨炎的疗效和安全性:一项法国全国多中心研究。
Ann Rheum Dis. 2018 Aug;77(8):1172-1178. doi: 10.1136/annrheumdis-2017-212705. Epub 2018 Mar 13.
4
Organ involvement pattern suggests subgroups within relapsing polychondritis: comment on the article by Dion et al.器官受累模式提示复发性多软骨炎存在亚组:对Dion等人文章的评论
Arthritis Rheumatol. 2018 Jan;70(1):148-149. doi: 10.1002/art.40330. Epub 2017 Nov 28.
5
(18)F-FDG PET-CT: a powerful tool for the diagnosis and treatment of relapsing polychondritis.(18)氟代脱氧葡萄糖正电子发射断层扫描-计算机断层扫描:用于复发性多软骨炎诊断和治疗的有力工具。
Br J Radiol. 2016;89(1057):20150695. doi: 10.1259/bjr.20150695. Epub 2015 Nov 3.
6
Utility of fluorodeoxyglucose positron emission tomography/computed tomography for early diagnosis and evaluation of disease activity of relapsing polychondritis: a case series and literature review.氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在复发性多软骨炎的早期诊断和疾病活动评估中的应用:病例系列及文献复习。
Rheumatology (Oxford). 2014 Aug;53(8):1482-90. doi: 10.1093/rheumatology/keu147. Epub 2014 Mar 27.
7
¹⁸F-FDG PET/CT is a valuable tool for relapsing polychondritis diagnose and therapeutic response monitoring.¹⁸F - FDG PET/CT是用于复发性多软骨炎诊断及治疗反应监测的一项有价值的工具。
Ann Nucl Med. 2014 Apr;28(3):276-84. doi: 10.1007/s12149-014-0805-1. Epub 2014 Jan 19.
8
Relapsing polychondritis: prospective study of 23 patients and a review of the literature.复发性多软骨炎:23例患者的前瞻性研究及文献综述
Medicine (Baltimore). 1976 May;55(3):193-215.