Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China.
J Magn Reson Imaging. 2024 Sep;60(3):827-847. doi: 10.1002/jmri.29114. Epub 2023 Nov 16.
Thyroid eye disease (TED) is a complex autoimmune disorder that impairs various orbital structures, leading to cosmetic damage and vision loss. Magnetic resonance imaging (MRI) is a fundamental diagnostic tool utilized in clinical settings of TED, for its accurate demonstration of orbital lesions and indication of disease conditions. The application of quantitative MRI has brought a new prospect to the management and research of TED, offering more detailed information on morphological and functional changes in the orbit. Therefore, many researchers concentrated on the implementation of different quantitative MRI techniques on TED for the exploration of clinical practices. Despite the abundance of studies utilizing quantitative MRI in TED, there remain considerable barriers and disputes on the best exploitation of this tool. This could possibly be attributed to the complexity of TED and the fast development of MRI techniques. It is necessary that clinical and radiological aspects of quantitative MRI in TED be better integrated into comprehensive insights. Hence, this review traces back 30 years of publications regarding quantitative MRI utilized in TED and elucidates this promising application in the facets of imaging techniques and clinical practices. We believe that a deeper understanding of the application of quantitative MRI in TED will enhance the efficacy of the multidisciplinary management of TED. LEVEL OF EVIDENCE: 2 TECHNICAL EFFICACY: Stage 3.
甲状腺眼病（TED）是一种复杂的自身免疫性疾病，会损害各种眼眶结构，导致外观受损和视力丧失。磁共振成像（MRI）是 TED 临床诊断中的基本工具，可准确显示眼眶病变并提示疾病状况。定量 MRI 的应用为 TED 的管理和研究带来了新的前景，为眼眶的形态和功能变化提供了更详细的信息。因此，许多研究人员专注于在 TED 中实施不同的定量 MRI 技术，以探索临床实践。尽管有大量研究利用 TED 中的定量 MRI，但在如何最好地利用该工具方面仍存在相当多的障碍和争议。这可能归因于 TED 的复杂性和 MRI 技术的快速发展。有必要将 TED 中定量 MRI 的临床和放射学方面更好地整合到全面的见解中。因此，本综述回溯了 30 年来有关 TED 中定量 MRI 应用的出版物，并从成像技术和临床实践方面阐述了这一很有前途的应用。我们相信，更深入地了解定量 MRI 在 TED 中的应用将提高 TED 多学科管理的效果。证据水平：2 技术功效：3 级。
