Zhang Haiyang, Chan Hoi Chi, Xu Jiashuo, Jiang Mengda, Tao Xiaofeng, Zhou Huifang, Song Xuefei, Fan Xianqun
Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China.
Sci Data. 2025 Jan 13;12(1):60. doi: 10.1038/s41597-025-04427-9.
This study presents TOM500, a comprehensive multi-organ annotated orbital magnetic resonance imaging (MRI) dataset. It includes clinical data, T2-weighted MRI scans, and corresponding segmentations from 500 patients with thyroid eye disease (TED) during their initial visit. TED is a common autoimmune disorder with distinct orbital MRI features. Segmentations of nine orbital structures, including the optic nerve, orbital fat, lacrimal gland, eyeball, and five extraocular muscles (superior rectus and levator palpebrae superioris complex, inferior rectus, medial rectus, lateral rectus, and superior oblique), were generated by three junior annotators and reviewed by an expert radiologist. The consistency of the segmentations was evaluated using the intraclass correlation coefficient. Clinical data, including sex, age, disease duration, and smoking status, are also provided for disease diagnosis and classification. TOM500, the largest publicly available orbital MRI dataset with expert annotations, is designed to facilitate the development of advanced computational tools for TED diagnosis, classification, and observation.
本研究展示了TOM500，这是一个全面的多器官注释眼眶磁共振成像（MRI）数据集。它包括临床数据、T2加权MRI扫描以及500例甲状腺眼病（TED）患者初诊时的相应分割图像。TED是一种常见的自身免疫性疾病，具有独特的眼眶MRI特征。九种眼眶结构的分割图像，包括视神经、眼眶脂肪、泪腺、眼球以及五条眼外肌（上直肌和上睑提肌复合体、下直肌、内直肌、外直肌和上斜肌），由三名初级注释人员生成，并由一名放射科专家进行审核。使用组内相关系数评估分割的一致性。还提供了包括性别、年龄、病程和吸烟状况在内的临床数据，用于疾病诊断和分类。TOM500是最大的公开可用且带有专家注释的眼眶MRI数据集，旨在促进用于TED诊断、分类和观察的先进计算工具的开发。
