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[奈图门与2-氰基乙基脲对大鼠白细胞计数的影响比较]

[The effect of Neythumun in comparison with 2-cyanoethylurea on the white blood count of the rat].

作者信息

von Ardenne M, Fleischer J, Reitnauer P G

出版信息

Pharmazie. 1986 Sep;41(9):651-2.

PMID:3797457
Abstract

The stimulation effect of Neythymun-Sol f+k (Nthy) and 2-Cyanethylcarbamide (CEC) on the leucocytopoesis was studied in 30 Wistar rats and a moderate but significant increase in the total number of leucocytes was found. The increase produced by CEC didn't prove significantly higher than that by Nthy. After 32 d the blood count showed a substantial difference concerning the neutrophils with an increase from 3000 to 9000 without deviation to the left, which was found only under Neythymun. This compound seems to be useful as a stimulator for the neutrophilic leucocytopoesis.

摘要

在30只Wistar大鼠中研究了Neythymun-Sol f+k(Nthy)和2-氰基乙基脲(CEC)对白细胞生成的刺激作用,发现白细胞总数有适度但显著的增加。CEC产生的增加并不显著高于Nthy产生的增加。32天后,血液计数显示中性粒细胞有显著差异,中性粒细胞从3000增加到9000,且无左移,这种情况仅在Neythymun作用下出现。该化合物似乎可用作嗜中性白细胞生成的刺激剂。

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